anti-Neurturin Antibody
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Catalog number1121
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoNeurturin Antibody: Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently and termed GDNFRβ, Ret ligand 2 (RETL2) or TGF-beta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRa;-2 recently. NTN binds to and forms a complex with GFRa;-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations. Neurturin and GDNF define a new family of neurotrophic factors.
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Gene namesNeurturin Antibody: NTN, Neurturin
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Antibodie s labelunlabelled serum
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PurityNeurturin Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenNeurturin antibody was made against a 16 amino acid peptide near the carboxy terminus of human Neurturin.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceNeurturin antibody can be used for detection of neurturin by Western blot. An approximate 14 kDa band of the full length recombinant NTN was detected. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
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Suspention pH azideNeurturin Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atNeurturin antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr4758826
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Ncbi nrNP_004549
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KDa14 kDa
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Vial with antibodyin solution
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NCBI GENE nr4902
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GENE symbolNRTN
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Antigene nameneurturin
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SourceHomo sapiens
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Protein nrQ99748
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNRTN
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Short nameanti-Neurturin Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toNeurturin (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameneurturin
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-05-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- GDNF family ligands
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data