NELF Antibody, Biotin Conjugated
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Catalog numberbs-11893R-Biotin
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PricePlease ask
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Size0.1ml
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Long nameNELF Polyclonal Antibody, Biotin Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationBiotin
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenNELF
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SpecificityThis is a highly specific antibody against NELF.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic peptide derived from human NELF
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Tested applicationsWB, IHC-P
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundNELF-A (negative elongation factor A), NELF-B, NELF-C, NELF-D and NELF-E are components of the NELF complex, which is a a structure that negatively regulates Pol II-dependent transcription elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b (P-TEFb) and negative transcription elongation factors, DSIF and NELF. DSIF and NELF, act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. DSIF/NELF inhibition of transcription is prevented by P-TEFb in cooperation with FACT.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation EmissionN/A
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SynonymsNasal embryonic LHRH factor; Nasal embryonic luteinizing hormone releasing hormone factor; Nasal embryonic luteinizing hormone-releasing hormone factor; Nelf; NELF_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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Additional conjugationBiotinylated
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French translationanticorps
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Gene target
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Gene symbolNSMF, NELFCD, NELFA, NELFB, NELFE
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Short nameAnti-NELF
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelBiotin
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Alternative nameAnti-NELF PAb Biotin
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameNMDA receptor synaptonuclear signaling and neuronal migration factor
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Synonyms gene
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Synonyms gene name
- nasal embryonic LHRH factor
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Locus
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Discovery year2004-03-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenegative elongation factor complex member C/D
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Synonyms gene
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Synonyms gene name
- TH1-like (Drosophila homolog)
- TH1-like (Drosophila)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-07-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Armadillo like helical domain containing
- Negative elongation factor complex members
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenegative elongation factor complex member A
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Synonyms gene
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Synonyms gene name
- Wolf-Hirschhorn syndrome candidate 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Negative elongation factor complex members
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenegative elongation factor complex member B
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Synonyms gene
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Synonyms gene name
- cofactor of BRCA1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-02-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Negative elongation factor complex members
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenegative elongation factor complex member E
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Synonyms gene
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Synonyms gene name
- RD RNA-binding protein
- RD RNA binding protein
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-11-18
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Entrez gene record
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Classification
- Negative elongation factor complex members
- MicroRNA protein coding host genes
- RNA binding motif containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data