NEDD8 Antibody

  • Catalog number
    F42040-0.4ML
  • Price
    Please ask
  • Size
    0.4 ml
  • Category
    Antibody
  • Concentration
    In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Form
    Purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    NEDD8
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, IHC, ELISA
  • Recommended dilutions
    Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
  • Notes
    Titration of the NEDD8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This NEDD8 antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    Q15843
  • Purity
    Purified
  • Description
    NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
  • Immunogen
    A portion of amino acids 1-32 from the human protein was used as the immunogen for this NEDD8 antibody.
  • Storage
    Aliquot the NEDD8 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    NEDD8  
  • Gene symbol
    NEDD8-MDP1, NEDD8
  • Short name
    Anti-NEDD8
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit Ig
  • Alternative name
    Antibodies to NEDD8
  • Alternative technique
    antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    NEDD8 ubiquitin like modifier
  • Synonyms gene name
    • neural precursor cell expressed, developmentally down-regulated 8
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1994-01-21
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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