MYLK3 Antibody

  • Catalog number
    bs-9865R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    MYLK3 Primary Polyclonal Antibody
  • Also known as
    MYLK3 PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    MYLK3
  • Specificity
    This is a highly specific antibody against MYLK3.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MYLK3
  • Tested Applications
    IHC-P, IF(IHC-P)
  • Recommended dilutions
    IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    caMLCK; Cardiac MyBP C associated Ca/CaM kinase; Cardiac-MyBP-C-associated Ca/CaM kinase; MLC kinase; MLCK; MLCK2; Mylk3; MYLK3_HUMAN; Myosin light chain kinase 3; Putative myosin light chain kinase 3.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    MYLK3  
  • Gene symbol
    MYLK3
  • Short name
    Anti-MYLK3
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Alternative name
    MYLK3 Polyclonal Antibody
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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