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Mucin Gastric Antibody ( 45M1)

  • Catalog number
    MA1061
  • Product name
    Mucin Gastric Antibody ( 45M1)
  • Size
    0,1 mg
  • Price
    320EUR
  • Supplier
    boster
  • Ask
  • Target antigen
    Mucin Gastric
  • Clonality
    Monoclonal antibody
  • Clone
    45M1
  • Raised in
    mice
  • Type of the antibody
    IgG1 monoclonal antibody
  • Product form
    freeze-dried
  • Reacts with species:
    Human, mouse, rabbit, rat
  • Analyses
    WB,IHC-P,ICC
  • Immunogen
    Mucin from human ovarian cyst fluid.
  • Product configuration
    Mouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
  • Purification
    Ascites
  • Solubilization
    The powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
  • Storage condtions
    Keep the Mucin Gastric Antibody ( 45M1)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
  • Tips
    The Mucin Gastric Antibody ( 45M1) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
  • Background
    Mucin 5AC (Muc5AC) is a protein that in humans is encoded by the MUC5AC gene. Using real-time RT-PCR, Moehle et al. (2006) found that MUC5AC was highly expressed in adult trachea and stomach. Expression was lower in adult lung and weak in fetal lung, and no expression was detected in other tissues. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease. Moreover, Muc5ac is identified as a direct and critical mediator of resistance during intestinal nematode infection.
  • Related articles
    1. Hasnain, S. Z., Evans, C. M., Roy, M., Gallagher, A. L., Kindrachuk, K. N., Barron, L., Dickey, B. F., Wilson, M. S., Wynn, T. A., Grencis, R. K., Thornton, D. J. Muc5ac: a critical component mediating the rejection of enteric nematodes. J. Exp. Med. 208: 893-900, 2011. 2. Moehle, C., Ackermann, N., Langmann, T., Aslanidis, C., Kel, A., Kel-Margoulis, O., Schmitz-Madry, A., Zahn, A., Stremmel, W., Schmitz, G. Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease. J. Molec. Med. 84: 1055-1066, 2006.
  • Gene Name
    MUC5AC
  • Protein Name
    Mucin-5AC
  • Gene Full Name
    mucin 5AC, oligomeric mucus/gel-forming
  • Synonyms
    Apomucin|Gastric mucin|LeB|Lewis B blood group antigen|Major Airway Glycoprotein|MUC 5|MUC5|MUC5AC|Mucin 5 subtype AC tracheobronchial|Mucin 5 Subtypes A And C|Mucin 5 subtypes A and C tracheobronchial/gastric|Mucin 5AC|Mucin 5AC oligomeric mucus/gel forming|Mucin 5AC, oligomeric mucus/gel forming pseudogene|TBM|Tracheobronchial Mucin
  • Uniprot ID
    Human(P98088)
  • Entrez GeneID
    Human(4586), Mouse(17833), Rat(682837)
  • Properties
    If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    Mucin Gastric Antibody ( 45M1)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    Mucin Gastric (Antibody to) ( 45M1)
  • Alternative technique
    antibodies
  • Ask
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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