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MEGF10 Antibody, Cy5 Conjugated

  • Long name
    MEGF10 Polyclonal Antibody, Cy5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy5
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    MEGF10
  • Specificity
    This is a highly specific antibody against MEGF10.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Subcellular location
    Extracellular
  • Source
    KLH conjugated synthetic peptide derived from human MEGF10
  • Gene ID number
    84466
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    625,650nm/670nm
  • Synonyms
    MEG10_HUMAN; MEGF protein; megf10; Multiple EGF-like domains protein 10; multiple EGF-like-domains 10; Multiple epidermal growth factor-like domains 10; Multiple epidermal growth factor-like domains protein 10.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
  • Additional conjugation
    Cy5.5
  • French translation
    anticorps
  • Gene target
  • Short name
    MEGF10 Antibody, Conjugated
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Label
    Cy5
  • Alternative name
    multiple epidermal growth factor-like-domains 10 (Antibody to), cyanine 5 coupled
  • Alternative technique
    antibodies
  • Alternative to gene target
    multiple EGF-like-domains 10, MEGF10 and IDBG-39569 and ENSG00000145794 and 84466, this GO :0001891 and pha this GO cytic cup and cellular component this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0014719 and satellite cell activation and biological process this GO :0014816 and satellite cell differentiation and biological process this GO :0014841 and satellite cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0034109 and homotypic cell-cell adhesion and biological process this GO :0042995 and cell projection and cellular component this GO :0043654 and recognition of apoptotic cell and biological process this GO :0048641 and regulation of skeletal muscle tissue development and biological process this GO :0051147 and regulation of muscle cell differentiation and biological process this GO :0055001 and muscle cell development and biological process, protein binding, this GO :0004866: endopeptidase inhibitor activity and also this GO :0005515: protein binding, this GO :0004866: endopeptidase inhibitor activity, this GO :0005515: protein binding, Plasma membranes, Megf10 and IDBG-148090 and ENSMUSG00000024593 and 70417, MEGF10 and IDBG-644881 and ENSBTAG00000000329 and 539136
MESH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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