MDM4 ANTIBODY
-
Catalog numberbs-7663R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameMDM4 Primary Polyclonal Antibody
-
Also known asMDM4 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenMDM4
-
SpecificityThis is a highly specific antibody against MDM4.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range300-330/490
-
Subcellular locationNucleus
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MDM4
-
Gene ID number4194
-
Swiss ProtO15151
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenInhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesHDMX; MDMX; MRP1; Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4; MDM4
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolMDM4
-
Short nameAnti-MDM4
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameMDM4 POLYCLONAL ANTIBODY
-
Alternative techniqueantibodies
-
Alternative to gene targetMdm4 p53 binding protein homolog (mouse), HDMX and MDMX and MRP1, MDM4 and IDBG-106054 and ENSG00000198625 and 4194, enzyme binding, nuclei, Mdm4 and IDBG-192393 and ENSMUSG00000054387 and 102641776,17248, BT.36413 and IDBG-628663 and ENSBTAG00000006255 and 100138492,514225
-
Gene info
-
Identity
-
Gene
-
Long gene nameMDM4 regulator of p53
-
Synonyms gene name
- mouse double minute 4, human homolog of; p53-binding protein
- Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)
- Mdm4 p53 binding protein homolog (mouse)
- MDM4, p53 regulator
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1997-09-05
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Ring finger proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data