LOX 1 Antibody, Cy5 Conjugated

  • Catalog number
    bs-2044R-Cy5
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    LOX 1 Polyclonal Antibody, Cy5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy5
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    LOX 1
  • Specificity
    This is a highly specific antibody against LOX 1.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen_range
    224-274/274
  • Subcellular location
    Extracellular
  • Source
    KLH conjugated synthetic peptide derived from Rabbit LOX-1
  • Gene ID number
    100009322
  • Swiss Prot
    Q9XTA8
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    625,650nm/670nm
  • Synonyms
    LOX1; LOX-1; Oxidized low-density lipoprotein receptor 1; Ox-LDL receptor 1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1; OLR1
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
  • Additional conjugation
    Cy5.5
  • French translation
    anticorps
  • Gene target
    LOX   Conjugated  
  • Gene symbol
    LOX, ALOX5, ALOX12B, ALOX12, ALOX15, ALOX15B, ALOXE3, OLR1
  • Short name
    Anti-LOX 1
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    Cy5
  • Alternative name
    Anti-LOX 1 PAb Cy5
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    arachidonate 15-lipoxygenase type B
  • Synonyms gene name
    • arachidonate 15-lipoxygenase, second type
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-07-22
  • Entrez gene record
    247
  • Pubmed identfication
  • Classification
    • Arachidonate lipoxygenases
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    oxidized low density lipoprotein receptor 1
  • Synonyms gene name
    • oxidised low density lipoprotein (lectin-like) receptor 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-01-16
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • C-type lectin domain containing
    • Scavenger receptors
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
  • Tree numbers
    • E05.393.220
  • Qualifiers
    drug effects, methods, radiation effects
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