LIM kinase 1 + 2 Antibody, Cy5 Conjugated

  • Catalog number
  • Product name
    LIM kinase 1 + 2 Antibody, Cy5 Conjugated
  • Size
  • Price
  • Supplier
    Bioss Primary Conjugated Antibodies
  • Long name
    LIM kinase 1 + 2 Polyclonal Antibody, Cy5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    LIM kinase 1 + 2
  • Specificity
    This is a highly specific antibody against LIM kinase 1 + 2.
  • Modification
  • Modification site
  • Clonality
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from human LIM kinase 1 + 2
  • Tested applications
  • Recommended dilutions
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    LIMK 1 and 2 likely regulate aspects of the cytoskeleton, through control of the organization of actin filaments. They can phosphorylate an actin-binding protein, cofilin which binds to actin monomers and polymers and promotes the disassembly of actin filament.The phosphorylation of cofilin via LIMK inactivates this potential. LIMK1 is highly active in the brain and spinal chord, where it is believed to be involved in the development of nerve cells whilst LIMK2 is ubiquitously expressed in many adult tissues. LIMK1 may play an important role in areas of the brain that are responsible for processing visual-spatial information (visuospatial constructive cognition). These parts of the brain are important for visualizing an object as a set of parts and performing tasks such as writing, drawing, constructing models, and assembling puzzles. LIMK1 is specifically stimulated by Rac, one of the Rho family proteins, while LIMK2 activity is activated under the control of other Rho family members, Rho and Cdc42, suggesting that two distinct pathways exist in the Rho family driven actin cytoskeleton dynamics.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
  • Synonyms
    LIM kinase 1+2; LIMK1+LIMK2; LIM domain kinase 1; LIM domain kinase 2; LIMK1; LIMK2;LIMK1_HUMAN; LIMK2_HUMAN.
  • group_crc32
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
  • Additional conjugation
  • French translation
  • Gene target
    LIM kinase 1 + 2 Conjugated 
  • Short name
    LIM kinase 1 + 2 Antibody, Conjugated
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Label
  • Alternative name
    LIM phosphorylation catalyst 1 and 2 (Antibody to), cyanine 5 coupled
  • Alternative technique
1. Gene info
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
Additional information
Related products
LIM kinase 1 + 2 Antibody, Cy5 Conjugated -
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