anti-LASS6 Antibody
-
Catalog number4941
-
PricePlease ask
-
Size0.02 mg, 0.1 mg
-
-
Gene infoLASS6 Antibody: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development.
-
Gene namesLASS6 Antibody: CERS5, LASS6, Ceramide synthase 6, LAG1 longevity assurance homolog 6, CerS6
-
Antibodie s labelunlabelled serum
-
PurityLASS6 Antibody is affinity chromatography purified via peptide column.
-
Ab raised inRabbit
-
TypePolyclonal
-
ImmunoglobulinIgG
-
Spicific toAt least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.
-
AntigenLASS6 antibody was made against a 13 amino acid synthetic peptide near the amino terminus of the human LASS6.
-
Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
-
Antibody adviceLASS6 antibody can be used for detection of LASS6 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
-
Suspention pH azideLASS6 Antibody is supplied in PBS containing 0.02% sodium azide.
-
Keep atLASS6 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
Works withHuman, Mouse, Rat
-
Omim nr80478334
-
Ncbi nrAAI09285
-
Vial with antibodyin solution
-
Quantity per ml1 mg/mL
-
NCBI GENE nr253782
-
GENE symbolLASS6
-
Antigene nameLAG1 homolog, ceramide synthase 6
-
SourceHomo sapiens
-
Protein nrQ6ZMG9
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolCERS6
-
Short nameanti-LASS6 Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toLASS6 (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameceramide synthase 6
-
Synonyms gene
-
Synonyms gene name
- LAG1 longevity assurance homolog 6 (S. cerevisiae)
- LAG1 homolog, ceramide synthase 6
-
GenBank acession
-
Locus
-
Discovery year2004-04-30
-
Entrez gene record
-
RefSeq identity
-
Classification
- CERS class homeoboxes
- MicroRNA protein coding host genes
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data