IL23 P19 Antibody

  • Catalog number
    PA1470
  • Price
    Please ask
  • Size
    0,1 mg
  • Target antigen
    IL23 P19 
  • Clonality
    Polyclonal antibody
  • Clone
    Polyclonal antibody
  • Raised in
    rabbit
  • Type of the antibody
    IgG polyclonal antibody
  • Product form
    freeze-dried
  • Reacts with species
    human
  • Analyses
    WB
  • Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of mouse IL23 P19(29-48aa DWAQCQQLSRNLCMLAWNAH), different from the related rat sequence by two amino acids.
  • Product configuration
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
  • Purification
    Immunogen affinity purified.
  • Solubilization
    The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
  • Storage condtions
    Keep the IL23 P19 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
  • Tips
    The IL23 P19 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
  • Background
    IL-23, Interleukin-23, also known as Interleukin-23 subunit alphainin(IL23A), is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19(the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.
  • Related articles
    1. Hu, W., Dehmel, T., Pirhonen, J., Hartung, H.-P., Kieseier, B. C.Interleukin 23 in acute inflammatory demyelination of the peripheral nerve.Arch. Neurol. 63: 858-864, 2006. 2. Kullberg, M. C., Jankovic, D., Feng, C. G., Hue, S., Gorelick, P. L., McKenzie, B. S., Cua, D. J., Powrie, F., Cheever, A. W., Maloy, K. J., Sher, A.IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.J. Exp. Med. 203: 2485-2494, 2006. 3. Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., Hunte, B., Vega, F., Yu, N., Wang, J., Singh, K., Zonin, F., Vaisberg, E., and 13 others.Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.Immunity 13: 715-725, 2000.
  • Gene Name
    IL23A
  • Protein Name
    Interleukin-23 subunit alpha(IL-23 subunit alpha/IL-23-A)
  • Gene Full Name
    interleukin 23, alpha subunit p19
  • Synonyms
    alpha subunit P19 antibody|IL-23 subunit alpha antibody|IL-23-A antibody|IL-23p19 antibody|IL23 antibody|IL23 P 19 antibody|IL23A antibody|IL23A_HUMAN antibody|IL23P19 antibody|interleukin 23 alpha subunit p19 antibody|interleukin 23 P19 subunit antibody|Interleukin-23 subunit alpha antibody|Interleukin-23 subunit p19 antibody|JKA3 induced upon T cell activation antibody|MGC79388 antibody|P19 antibody|SGRF antibody
  • Uniprot ID
    Q9EQ14
  • Properties
    If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    IL23   P19   
  • Gene symbol
    H3P13, CDKN2D, IL23A, CDKN2A
  • Short name
    IL23 P19 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    IL23 P19 (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    cyclin dependent kinase inhibitor 2D
  • Synonyms gene name
    • cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • Synonyms
  • Locus
  • Discovery year
    1995-07-06
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Ankyrin repeat domain containing
  • VEGA ID
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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