IL23 P19 Antibody
-
Catalog numberPA1470
-
PricePlease ask
-
Size0,1 mg
-
-
Target antigenIL23 P19
-
ClonalityPolyclonal antibody
-
ClonePolyclonal antibody
-
Raised inrabbit
-
Type of the antibodyIgG polyclonal antibody
-
Product formfreeze-dried
-
Reacts with specieshuman
-
AnalysesWB
-
ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of mouse IL23 P19(29-48aa DWAQCQQLSRNLCMLAWNAH), different from the related rat sequence by two amino acids.
-
Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
-
PurificationImmunogen affinity purified.
-
SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
-
Storage condtionsKeep the IL23 P19 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
-
TipsThe IL23 P19 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
-
BackgroundIL-23, Interleukin-23, also known as Interleukin-23 subunit alphainin(IL23A), is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19(the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.
-
Related articles1. Hu, W., Dehmel, T., Pirhonen, J., Hartung, H.-P., Kieseier, B. C.Interleukin 23 in acute inflammatory demyelination of the peripheral nerve.Arch. Neurol. 63: 858-864, 2006. 2. Kullberg, M. C., Jankovic, D., Feng, C. G., Hue, S., Gorelick, P. L., McKenzie, B. S., Cua, D. J., Powrie, F., Cheever, A. W., Maloy, K. J., Sher, A.IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.J. Exp. Med. 203: 2485-2494, 2006. 3. Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., Hunte, B., Vega, F., Yu, N., Wang, J., Singh, K., Zonin, F., Vaisberg, E., and 13 others.Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.Immunity 13: 715-725, 2000.
-
Gene NameIL23A
-
Protein NameInterleukin-23 subunit alpha(IL-23 subunit alpha/IL-23-A)
-
Gene Full Nameinterleukin 23, alpha subunit p19
-
Synonymsalpha subunit P19 antibody|IL-23 subunit alpha antibody|IL-23-A antibody|IL-23p19 antibody|IL23 antibody|IL23 P 19 antibody|IL23A antibody|IL23A_HUMAN antibody|IL23P19 antibody|interleukin 23 alpha subunit p19 antibody|interleukin 23 P19 subunit antibody|Interleukin-23 subunit alpha antibody|Interleukin-23 subunit p19 antibody|JKA3 induced upon T cell activation antibody|MGC79388 antibody|P19 antibody|SGRF antibody
-
Uniprot IDQ9EQ14
-
PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolH3P13, CDKN2D, IL23A, CDKN2A
-
Short nameIL23 P19 Antibody
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
Alternative nameIL23 P19 (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameH3 histone pseudogene 13
-
Synonyms
-
Locus
-
Discovery year2019-08-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
Gene info
-
Identity
-
Gene
-
Long gene namecyclin dependent kinase inhibitor 2D
-
Synonyms gene name
- cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
-
Synonyms
-
Locus
-
Discovery year1995-07-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Ankyrin repeat domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 23 subunit alpha
-
Synonyms gene name
- interleukin 23, alpha subunit p19
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-04-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecyclin dependent kinase inhibitor 2A
-
Synonyms gene
-
Synonyms gene name
- cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1994-05-19
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data