ID2 Antibody, Cy3 Conjugated

• Catalog number
  bs-3515R-Cy3
• Price
  Please ask
• Size
  0.1ml

• Long name
  ID2 Polyclonal Antibody, Cy3 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy3
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  ID2
• Specificity
  This is a highly specific antibody against ID2. Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77% sequence similarity in the range of our immunogen.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  33-82/134
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from human GIG8/ID2
• Gene ID number
  3398
• Swiss Prot
  Q02363
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  512,550nm/570,615nm
• Synonyms
  GIG8; ID2A; ID2H; bHLHb26; DNA-binding protein inhibitor ID-2; Class B basic helix-loop-helix protein 26; Inhibitor of DNA binding 2; Inhibitor of differentiation 2; ID2
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-ID2 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
• Additional conjugation
  cy3 conjugation kit
• French translation
  anticorps

• Gene target
  ID2   Conjugated  
• Gene symbol
  ID2-AS1, ID2
• Short name
  Anti-ID2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy3
• Alternative name
  Anti-ID2 PAb Cy3
• Alternative technique
  antibodies
• Alternative to gene target
  inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, bHLHb26 and GIG8 and ID2A and ID2H, ID2 and IDBG-27111 and ENSG00000115738 and 3398, protein dimerization activity, nuclei, Id2 and IDBG-131550 and ENSMUSG00000020644 and 15902, ID2 and IDBG-638503 and ENSBTAG00000021187 and 505025

Gene info

• Identity
  HGNC:51103
• Gene
  ID2-AS1
• Long gene name
  ID2 antisense RNA 1
• Synonyms gene name
  • ID2 antisense RNA 1 (head to head)
• Locus
  2p25.1
• Discovery year
  2014-07-29
• Entrez gene record
  100506299
• RefSeq identity
  • NR_110153
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000151625

Gene info

• Identity
  HGNC:5361
• Gene
  ID2
• Long gene name
  inhibitor of DNA binding 2
• Synonyms gene name
  • inhibitor of differentiation 2
  • inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
• Synonyms
  • GIG8
  • bHLHb26
• Synonyms name
  • cell growth-inhibiting gene 8
• Locus
  2p25.1
• Discovery year
  1994-12-22
• Entrez gene record
  3398
• Pubmed identfication
  • 8294468
• RefSeq identity
  • NM_002166
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000112454

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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