HSF1(Ser307) Antibody

• Catalog number
  bs-5364R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HSF1(Ser307) Primary Polyclonal Antibody
• Also known as
  HSF1(Ser307) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HSF1 Ser307
• Specificity
  This is a highly specific antibody against HSF1 Ser307.
• Modification s
  Phosphorylation
• Modification site s
  Ser307
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human HSF1 around the phosphorylation site of Ser303
• Gene ID number
  3297
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Two HSFs have been identified in human cells, HSF 1 and HSF 2, which bind to the same HSEs and have 38% sequence identity. These factors are activated by distinct stimuli, HSF 1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF 2 is activated during hemin-mediated differentiation of human erythroleukemia cells.HSF 1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity. Through an unknown signal generated during stress, HSF 1 becomes activated to a nuclear localized, trimeric state which binds to DNA. The phosphorylation of HSF 1 is necessary for maximal transcription of heat shock genes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  HSF1 Ser307; Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1; hsf1; HSTF 1; HSTF1; HSF1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HSF1   Ser307  
• Gene symbol
  HSF1
• Short name
  Anti-HSF1 Ser307
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HSF1(Ser307) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  heat shock transcription factor 1, HSTF1, HSF1 and IDBG-40498 and ENSG00000185122 and 3297, sequence-specific DNA binding, nuclei, Hsf1 and IDBG-155311 and ENSMUSG00000022556 and 15499, HSF1 and IDBG-643592 and ENSBTAG00000020751 and 506235

Gene info

• Identity
  HGNC:5224
• Gene
  HSF1
• Long gene name
  heat shock transcription factor 1
• Synonyms
  • HSTF1
• GenBank acession
  • M64673
• Locus
  8q24.3
• Discovery year
  1994-09-12
• Entrez gene record
  3297
• Pubmed identfication
  • 1871105
• RefSeq identity
  • NM_005526
• VEGA ID
  OTTHUMG00000174604

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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