Type of the antibody
IgG polyclonal antibody
Reacts with species:
human, mouse, rat
E.coli-derived human Hsc70 recombinant protein (Position: Q520-A614). Human Hsc70 shares 98.9% amino acid (aa) sequence identity with both mouse and rat Hsc70.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen affinity purified.
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Keep the Hsc70 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
The Hsc70 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
HSPA8 (heat shock 70kDa protein 8) also known as HSC70, HSC71, HSP73, HSPA10, FORMERLY, LAP1 or LPS-ASSOCIATED PROTEIN 1, is a heat shock protein that in humans is encoded by the HSPA8 gene. The HSPA8 gene contains 9 exons and spans 5 kb. The deduced HSPA8 protein has 646 amino acids and a predicted molecular mass of 70,899 Da. And the HSPA8 gene is mapped on 11q24.1. HSPA8 plays an important role in cells by transiently associating with nascent polypeptides to facilitate correct folding. HSP73 also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Rapid decay involves AU-rich binding protein AUF1, which complexes with heat-shock proteins HSC70 and HSP70, translation initiation factor EIF4G, and poly (A)-binding protein. In the absence of Il3, Hsc70 formed a complex with Hsp40 and Hip, and this complex, in association with Eif4g and Pabp, formed a high-stability complex with Bim mRNA that protected it from ribonucleases.
1. Chappell, T. G., Welch, W. J., Schlossman, D. M., Palter, K. B., Schlesinger, M. J., Rothman, J. E. Uncoating ATPase is a member of the 70 kilodalton family of stress proteins. Cell 45: 3-13, 1986. 2. Hohfeld, J., Minami, Y., Hartl, F.-U. Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle. Cell 83: 589-598, 1995. 3. Matsui, H., Asou, H., Inaba, T. Cytokines direct the regulation of Bim mRNA stability by heat-shock cognate protein 70. Molec. Cell 25: 99-112, 2007.
Heat shock cognate 71 kDa protein
Gene Full Name
heat shock 70kDa protein 8
2410008N15Rik antibody|Constitutive heat shock protein 70 antibody|Heat shock 70 kDa protein 8 antibody|Heat shock 70kD protein 10 antibody|Heat shock 70kD protein 8 antibody| Heat shock 70kDa protein 8 antibody|Heat shock cognate 71 kDa protein antibody| Heat shock cognate 71 kDa protein. antibody|Heat shock cognate protein 54 antibody|Heat shock cognate protein 71 kDa antibody|Heat shock cognate protein 71-kDa antibody|Heat shock protein 8 antibody|Heat shock protein A8 antibody|Heat-shock70-KD protein 10, formerly antibody|HSC54 antibody|HSC71 antibody|Hsc73 antibody|HSP71 antibody|HSP73 antibody|HSP7C_HUMAN antibody| HSPA10 antibody|HSPA8 antibody|LAP1 antibody|Lipopolysaccharide associated protein 1 antibody|LPS associated protein 1 antibody|LPS associated protein antibody|MGC102007 antibody|MGC106514 antibody|MGC114311 antibody|MGC118485 antibody|MGC131511 antibody| MGC29929 antibody|N-myristoyltransferase inhibitor protein 71 antibody|NIP71 antibody
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.