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GORASP2/Golgi phosphoprotein 6/GRASP55 Antibody, Cy3 Conjugated

  • Catalog number
    bs-13492R-Cy3
  • Product name
    GORASP2/Golgi phosphoprotein 6/GRASP55 Antibody, Cy3 Conjugated
  • Size
    0.1ml
  • Price
    350EUR
  • Supplier
    Bioss Primary Conjugated Antibodies
  • Ask
  • Clonality
    Polyclonal
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Antigen background
    The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
  • Modification site
    None
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Long name
    GORASP2/Golgi phosphoprotein 6/GRASP55 Antibody, Cy3 Conjugated
  • Synonyms
    AW552058; DKFZp434D156; FLJ13139; Golgi phosphoprotein 6; Golgi reassembly stacking protein 2; Golgi reassembly stacking protein 2, 55kDa; Golgi reassembly stacking protein of 55 kDa; Golgi reassembly-stacking protein 2; Golgi reassembly-stacking protein of 55 kDa; GOLPH2; GOLPH6; GORASP2; GORS2_HUMAN; GRASP55; GRS2; p59; RP23-428O15.1.
  • Gene ID number
    26003
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Conjugation
    Cy3
  • Modification
    Unmodified
  • Category
    Conjugated Primary Antibodies
  • Source
    KLH conjugated synthetic peptide derived from human Golgi phosphoprotein 6
  • Specificity
    This is a highly specific antibody against Golgi phosphoprotein 6.
  • Tested applications
    IF(IHC-P)
  • Clone
    Polyclonal antibody
  • Crossreactivity
    Human, Mouse, Rat
  • Concentration
    1ug per 1ul
  • Target Antigen
    Golgi phosphoprotein 6
  • Excitation Emission
    512,550nm/570,615nm
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the GORASP2/Golgi phosphoprotein 6/GRASP55 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
  • Additional conjugation
    cy3 conjugation kit
  • Gene target
  • Short name
    GORASP2/Golgi phosphoprotein 6/GRASP55 Antibody, Conjugated
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Label
    Cy3
  • Alternative name
    GORASP2/vesicle packing phosphoprotein 6/GRASP55 (Antibody to), cyanine 3 coupled
  • Alternative technique
    antibodies
  • Ask
1. Gene info
  • Identity
  • Gene
  • Long gene name
    golgi reassembly stacking protein 2
  • Synonyms gene name
    • golgi reassembly stacking protein 2, 55 kDa
    • golgi reassembly stacking protein 2, 55kDa
  • Synonyms
  • Locus
  • Discovery year
    2002-05-23
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • PDZ domain containing
  • Havana BLAST/BLAT
2. Gene info
  • Identity
  • Gene
  • Long gene name
    fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2)
  • Locus
  • Discovery year
    1986-01-01
  • Pubmed identfication
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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