GDNF Antibody
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Catalog numberR30537
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenGDNF
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC-P, ICC
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Recommended dilutionsWestern blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
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NotesThe stated application concentrations are suggested starting amounts. Titration of the GDNF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis GDNF antibodyis to be used only for research purposes and not for diagnostics..
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UniprotP39905
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PurityAntigen affinity
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DescriptionGlial cell-derived neurotrophic factor, is a protein that, in humans, is encoded by the GDNF gene. It is a small protein that potently promotes the survival of many types of neurons and a founding member of the GDNF family of ligands(GFL). The gene is mapped to human chromosome 5p13.1-p12 by fluorescence in situ hybridization(FISH). This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosisof motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET(rearranged during transfection) protooncogene.
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ImmunogenAn amino acid sequence from the middle region of human GDNF (FRYCSGSCDAAETTYDK) was used as the immunogen for this GDNF antibody.
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StorageAfter reconstitution, the GDNF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolGDNF, GDNF-AS1
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Short nameAnti-GDNF
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to GDNF
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Alternative techniqueantibodies
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Alternative to gene targetglial cell derived neurotrophic factor, ATF1 and ATF2 and HFB1-GDNF and HSCR3, GDNF and IDBG-17169 and ENSG00000168621 and 2668, protein homodimerization activity, Extracellular, Gdnf and IDBG-128378 and ENSMUSG00000022144 and 14573, BT.58072 and IDBG-630047 and ENSBTAG00000005176 and 386587
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Gene info
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Identity
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Gene
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Long gene nameglial cell derived neurotrophic factor
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Synonyms
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Synonyms name
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Locus
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Discovery year1995-05-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- GDNF family ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameGDNF antisense RNA 1
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Synonyms gene name
- GDNF antisense RNA 1 (non-protein coding)
- GDNF antisense RNA 1
- GDNF antisense RNA 1 (head to head)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2011-11-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data