Endomucin Antibody

• Catalog number
  R32349
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Endomucin
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the Endomucin antibody should be determined by the researcher.
• Intented use
  This Endomucin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9ULC0
• Purity
  Antigen affinity
• Description
  Endomucin is a protein that in humans is encoded by the EMCN gene. It is mapped to 4q24. EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. Using suppression subtractive hybridization (SSH), people found endomucin a potential cell surface marker upregulated. Human endomucin is predicted to encode a 261-aa, 27.5-kDa protein with a transmembrane sequence and multiple glycosylation sites. Northern and in situ hybridization studies show that human endomucin expression is largely, if not uniquely, endothelial cell-specific. And human endomucin is present abundantly in highly vascular tissues such as heart, kidney, and lung.
• Immunogen
  Amino acids ENGNDQPQSDKESVKLLTVKTISHESGEHSAQGK of human EMCN were used as the immunogen for the Endomucin antibody.
• Storage
  After reconstitution, the Endomucin antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Endomucin  
• Gene symbol
  EMCN
• Short name
  Anti-Endomucin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Endomucin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16041
• Gene
  EMCN
• Long gene name
  endomucin
• Synonyms
  • MUC14
• GenBank acession
  • AF205940
• Locus
  4q24
• Discovery year
  2006-04-03
• Entrez gene record
  51705
• Pubmed identfication
  • 11418125
  • 11594763
• RefSeq identity
  • NM_016242
• Classification
  • Mucins
• VEGA ID
  OTTHUMG00000131051

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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