DUX4 Antibody, Cy7 Conjugated

• Catalog number
  bs-12369R-Cy7
• Price
  Please ask
• Size
  0.1ml

• Long name
  DUX4 Polyclonal Antibody, Cy7 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy7
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DUX4
• Specificity
  This is a highly specific antibody against DUX4.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human DUX4
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  DUX4 is a homeodomain protein with a similar protein sequence to Pax3 and Pax7. Defects in DUX4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD). FSHD is characterized by weakness of the muscles of the face, upper-arm and shoulder girdle. Severity is highly variable. Weakness is slowly progressive and about 20% of affected individuals eventually require a wheelchair. Approximately 70-90% of individuals have inherited the disease-causing deletion from a parent, and approximately 10-30% of affected individuals have FSHD as the result of a de novo deletion. Offsprings of an affected individual have a 50% chance of inheriting the deletion.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  743nm/767nm
• Synonyms
  Double homeobox protein 10; Double homeobox protein 4; Double homeobox protein 4/10; DUX10; DUX4_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugated
  These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
• Additional conjugation
  Cy7
• French translation
  anticorps

• Gene target
  DUX4   Conjugated  
• Gene symbol
  DUX4, DUX4L1
• Short name
  Anti-DUX4
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy7
• Alternative name
  Anti-DUX4 PAb Cy7
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:50800
• Gene
  DUX4
• Long gene name
  double homeobox 4
• Locus
  4q35.2
• Discovery year
  2014-06-20
• Entrez gene record
  100288687
• Pubmed identfication
  • 20724583
• VEGA ID
  OTTHUMG00000175568
• Locus Specific Databases
  • LRG_1075

Gene info

• Identity
  HGNC:3082
• Gene
  DUX4L1
• Long gene name
  double homeobox 4 like 1 (pseudogene)
• Synonyms gene
  • DUX4
• Synonyms gene name
  • double homeobox 4
  • double homeobox 4 like 1
• GenBank acession
  • D38024
• Locus
  4q35.2
• Discovery year
  1999-12-01
• Entrez gene record
  22947
• RefSeq identity
  • NG_034172
• Classification
  • PRD class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000161317

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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