Dnmt3a Antibody

• Catalog number
  F40558-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Dnmt3a
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the Dnmt3a antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Dnmt3a antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9Y6K1
• Purity
  Purified
• Description
  CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
• Immunogen
  A portion of amino acids 723-752 from the human protein was used as the immunogen for this Dnmt3a antibody.
• Storage
  Aliquot the Dnmt3a antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Dnmt3a  
• Gene symbol
  DNMT3A, LINC01381
• Short name
  Anti-Dnmt3a
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Dnmt3a
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2978
• Gene
  DNMT3A
• Long gene name
  DNA methyltransferase 3 alpha
• Synonyms gene name
  • DNA (cytosine-5-)-methyltransferase 3 alpha
• Locus
  2p23.3
• Discovery year
  1998-07-15
• Entrez gene record
  1788
• Pubmed identfication
  • 9662389
  • 10433969
• RefSeq identity
  • NM_022552
• Classification
  • MicroRNA protein coding host genes
  • 7BS C5-cytosine DNA/RNA methyltransferases
  • PWWP domain containing
• VEGA ID
  OTTHUMG00000094777
• Locus Specific Databases
  • LRG_459

Gene info

• Identity
  HGNC:50653
• Gene
  LINC01381
• Long gene name
  long intergenic non-protein coding RNA 1381
• Synonyms
  • TCONS_00002860
  • DADOT
• Synonyms name
  • DNMT3A antisense downstream transcript
• GenBank acession
  • AW515644
• Locus
  2p23.3
• Discovery year
  2014-06-04
• Entrez gene record
  106144568
• Classification
  • Long intergenic non-protein coding RNAs
• VEGA ID
  OTTHUMG00000152010

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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