DMP1 Antibody

• Catalog number
  bs-12359R
• Price
  Please ask
• Size
  0.1ml

• Long name
  DMP1 Primary Polyclonal Antibody
• Also known as
  DMP1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  DMP1
• Specificity
  This is a highly specific antibody against DMP1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DMP1
• Gene ID number
  1758
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  DMP-1 is a member of the small integrin ligand N-linked glycoprotein family. It is important for the mineralization of bone and dentin. DMP-1 is expressed in bone, tooth and hypertrophic cartilage. It is synthesized by preosteoblasts and contains a large number of acidic domains. DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation. During osteoblast maturation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus. DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue. DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin. The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate.The loss of DMP-1 can result in hypomineralized bone.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ARHP; ARHR; AV020965; Dentin matrix acidic phosphoprotein 1; Dentin matrix protein 1; DENTMAT; DMP 1; Dmp; MGC130441; PP; Serine rich acidic phosphoprotein; DMP1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DMP1  
• Gene symbol
  DMP1, DMTF1
• Short name
  Anti-DMP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  DMP1 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  dentin matrix acidic phosphoprotein 1, ARHP and ARHR and DMP-1, DMP1 and IDBG-29190 and ENSG00000152592 and 1758, extracellular matrix binding, nuclei, Dmp1 and IDBG-185392 and ENSMUSG00000029307 and 13406, DMP1 and IDBG-643326 and ENSBTAG00000019132 and 281118

Gene info

• Identity
  HGNC:2932
• Gene
  DMP1
• Long gene name
  dentin matrix acidic phosphoprotein 1
• Synonyms gene name
  • dentin matrix acidic phosphoprotein
• GenBank acession
  • U34037
• Locus
  4q22.1
• Discovery year
  1995-08-10
• Entrez gene record
  1758
• Pubmed identfication
  • 8586437
  • 9177774
• Classification
  • SIBLING family
• VEGA ID
  OTTHUMG00000130598

Gene info

• Identity
  HGNC:14603
• Gene
  DMTF1
• Long gene name
  cyclin D binding myb like transcription factor 1
• Synonyms gene name
  • cyclin D binding myb-like transcription factor 1
• Synonyms
  • DMP1
  • DMTF
  • hDMP1
  • MRUL
• Synonyms name
  • cyclin D-binding Myb-like protein
• GenBank acession
  • AF084530
• Locus
  7q21.12
• Discovery year
  2001-02-28
• Entrez gene record
  9988
• Pubmed identfication
  • 10095122
  • 24958102
• RefSeq identity
  • NM_021145
• Classification
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000154135

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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