DKK1 Antibody

• Catalog number
  R30534
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  DKK1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the DKK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This DKK1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O94907
• Purity
  Antigen affinity
• Description
  Dickkopf-related protein 1 is a protein that in humans is encoded by the DKK1 gene. This gene encodes a protein that is a member of the dickkopf family. By genomic sequence analysis, determined that the gene contains 4 exons. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
• Immunogen
  An amino acid sequence from the N-terminus of human DKK1 (YPGGNKYQTIDNYQPY) was used as the immunogen for this DKK1 antibody.
• Storage
  After reconstitution, the DKK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DKK1  
• Gene symbol
  DKK1
• Short name
  Anti-DKK1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to DKK1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2891
• Gene
  DKK1
• Long gene name
  dickkopf WNT signaling pathway inhibitor 1
• Synonyms gene name
  • dickkopf (Xenopus laevis) homolog 1
  • dickkopf 1 homolog (Xenopus laevis)
• Synonyms
  • SK
  • DKK-1
• Locus
  10q21.1
• Discovery year
  2000-09-01
• Entrez gene record
  22943
• RefSeq identity
  • NM_012242
• VEGA ID
  OTTHUMG00000018247

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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