Chloride Channel 5 Antibody, ALEXA FLUOR 555
Chloride Channel 5 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Also known as
Anti-Chloride Channel 5 PAb ALEXA FLUOR 555
Conjugated Primary Antibodies
ALEXA FLUOR® 555
Rabbit (Oryctolagus cuniculus)
Chloride Channel 5
This is a highly specific antibody against Chloride Channel 5.
1ug per 1ul
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5
Human, Mouse, Rat
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dentâ€™s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
Purified by Protein A.
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Chloride channel protein 5; Chloride transporter ClC-5; ClC-5; CLC5; CLCK2; CLCN5; CLCN5_HUMAN; DENTS; H+/Cl- exchange transporter 5; hCIC-K2; NPHL1; NPHL2; XLRH; XRN.
For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Alexa Fluor, ALEXA FLUOR 555
Chloride Channel 5 Antibody,
Antibody, antibodies against human proteins, antibodies for
ALEXA FLUOR 555
Chloride Channel 5 (Antibody to), ALEXA FLUOR 555
1. Gene info
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics