CDK1 Antibody, Biotin Conjugated

  • Catalog number
    bs-0542R-Biotin
  • Product name
    CDK1 Antibody, Biotin Conjugated
  • Size
    0.1ml
  • Price
    393.14
  • Supplier
    Bioss Primary Conjugated Antibodies
  • Long name
    CDK1 Polyclonal Antibody, Biotin Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Biotin
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    CDK1
  • Specificity
    This is a highly specific antibody against CDK1.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen_range
    250-297/297
  • Subcellular location
    Cytoplasm, Nucleus, Mitochondrion
  • Source
    KLH conjugated synthetic peptide derived from mouse CDK1
  • Gene ID number
    12534
  • Swiss Prot
    P11440
  • Tested applications
    WB, IHC-P
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    N/A
  • Synonyms
    Cdc2; Cdc2a; p34; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase; Cdkn1
  • group_crc32
    1731266212
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
  • Additional conjugation
    Biotinylated
  • French translation
    anticorps
  • Gene target
  • Short name
    CDK1 Antibody, Conjugated
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Label
    Biotin
  • Alternative name
    cyclin-dependent kinase 1 (Antibody to), biotinilated coupled
  • Alternative technique
    antibodies
  • Alternative to gene target
    cyclin-dependent kinase 1, CDC2 and CDC28A and P34CDC2, CDK1 and IDBG-75344 and ENSG00000170312 and 983, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000083 and regulation of transcription involved in G1/S transition of mitotic cell cycle and biological process this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0000226 and microtubule cytoskeleton organization and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004693 and cyclin-dependent protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005876 and spindle microtubule and cellular component this GO :0006260 and DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007077 and mitotic nuclear envelope disassembly and biological process this GO :0007095 and mitotic G2 DNA damage checkpoint and biological process this GO :0007098 and centrosome cycle and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007344 and pronuclear fusion and biological process this GO :0007411 and axon guidance and biological process this GO :0007569 and cell aging and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008353 and RNA polymerase II carboxy-terminal domain kinase activity and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009636 and response to toxic substance and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0014038 and regulation of Schwann cell differentiation and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014075 and response to amine and biological process this GO :0014823 and response to activity and biological process this GO :0016020 and membrane and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016477 and cell migration and biological process this GO :0016572 and histone phosphorylation and biological process this GO :0016772 and transferase activity, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0030261 and chromosome condensation and biological process this GO :0030332 and cyclin binding and molecular function this GO :0030496 and midbody and cellular component this GO :0030544 and Hsp70 protein binding and molecular function this GO :0030855 and epithelial cell differentiation and biological process this GO :0031100 and organ regeneration and biological process this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0033160 and positive regulation of protein import into nucleus, translocation and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0034501 and protein localization to kinetochore and biological process this GO :0035173 and histone kinase activity and molecular function this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0045995 and regulation of embryonic development and biological process this GO :0046686 and response to cadmium ion and biological process this GO :0046688 and response to copper ion and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048678 and response to axon injury and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0055015 and ventricular cardiac muscle cell development and biological process this GO :0060045 and positive regulation of cardiac muscle cell proliferation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0072686 and mitotic spindle and cellular component, transferase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004693: cyclin-dependent protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008353: RNA polymerase II carboxy-terminal domain kinase activity and also this GO :0016301: kinase activity and also this GO :0016772: transferase activity, transferring phosphorus-containing groups and also this GO :0030332: cyclin binding and also this GO :0030544: Hsp70 protein binding and also this GO :0035173: histone kinase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004693: cyclin-dependent protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008353: RNA polymerase II carboxy-terminal domain kinase activity, this GO :0016301: kinase activity, this GO :0016772: transferase activity, transferring phosphorus-containing groups, this GO :0030332: cyclin binding, this GO :0030544: Hsp70 protein binding, this GO :0035173: histone kinase activity, nuclei, Cdk1 and IDBG-160472 and ENSMUSG00000019942 and 12534, CDK1 and IDBG-628960 and ENSBTAG00000010109 and 281061
1. Gene info
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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