CD82 Antibody

• Catalog number
  PA1307
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  CD82
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  solution
• Reacts with species
  human
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human CD82(253-267aa CRHVHSEDYSKVPKY), different from the related mouse and rat sequences by two amino acids.
• Product configuration
  Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4.
• Purification
  Immunogen affinity purified.
• Solubilization
  solution
• Storage condtions
  Keep the CD82 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The CD82 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  CD82(Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma(ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.
• Related articles
  1. Dong, J.-T.; Lamb, P. W.; Rinker-Schaeffer, C. W.; Vukanovic, J.; Ichikawa, T.; Isaacs, J. T.; Barrett, J. C. : KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science 268: 884-886, 1995. 2. Mashimo, T.; Watabe, M.; Hirota, S.; Hosobe, S.; Miura, K.; Tegtmeyer, P. J.; Rinker-Shaeffer, C. W.; Watabe, K. : The expression of the KAI1 gene, a tumor metastasis suppressor, is directly activated by p53. Proc. Nat. Acad. Sci. 95: 11307-11311, 1998. 3. Miyazaki, T.; Kato, H.; Shitara, Y.; Yoshikawa, M.; Tajima, K.; Masuda, N.; Shouji, H.; Tsukada, K.; Nakajima, T.; Kuwano, H. : Mutation and expression of the metastasis suppressor gene KAI1 in esophageal squamous cell carcinoma. Cancer 89: 955-962, 2000. 4. Jee, B. K.; Park, K. M.; Surendran, S.; Lee, W. K.; Han, C. W.; Kim, Y. S.; Lim, Y. : KAI1/CD82 suppresses tumor invasion by MMP9 inactivation via TIMP1 up-regulation in the H1299 human lung carcinoma cell line. Biochem. Biophys. Res. Commun. 342: 655-661, 2006.
• Gene Name
  CD82
• Protein Name
  CD82 antigen
• Gene Full Name
  CD82 molecule
• Synonyms
  4F9 antibody|Antigen detected by monoclonal and antibody IA4 antibody|C33 antibody|C33 antigen antibody|CD 82 antibody|CD82 antibody|Cd82 antibody|CD82 antigen antibody|CD82 molecule antibody|CD82_HUMAN antibody|GR 15 antibody|GR15 antibody|IA 4 antibody|IA4 antibody|Inducible membrane protein antibody|Inducible membrane protein R2 antibody|KAI 1 antibody|KAI1 antibody|Kangai 1(suppression of tumorigenicity 6, prostate; CD82 antigen(R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4) antibody|Kangai 1 antibody|Kangai1 antibody|Metastasis suppressor Kangai 1 antibody|Metastasis suppressor Kangai-1 antibody|Metastasis suppressor Kangai1 antibody|R2 antibody|R2 leukocyte antigen antibody|SAR 2 antibody|SAR2 antibody|ST 6 antibody|ST6 antibody|Suppression of tumorigenicity 6 antibody|Suppression of tumorigenicity 6 prostate antibody|Suppressor of tumorigenicity 6 antibody|Suppressor of tumorigenicity 6 protein antibody|Tetraspanin 27 antibody|Tetraspanin-27 antibody|Tetraspanin27 antibody|Tspan 27 antibody|Tspan-27 antibody|Tspan27 antibody
• Uniprot ID
  P27701
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD82  
• Gene symbol
  CD82
• Short name
  CD82 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  CD82 molecule (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  CD82 molecule, 4F9 and C33 and GR15 and IA4 and KAI1 and R2 and SAR2 and ST6 and TSPAN27, CD82 and IDBG-40873 and ENSG00000085117 and 3732, protein binding, Plasma membranes, Cd82 and IDBG-192552 and ENSMUSG00000027215 and 12521, CD82 and IDBG-636903 and ENSBTAG00000031252 and 100335281,506713

Gene info

• Identity
  HGNC:6210
• Gene
  CD82
• Long gene name
  CD82 molecule
• Synonyms gene
  • ST6
  • KAI1
• Synonyms gene name
  • kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
  • CD82 antigen
• Synonyms
  • R2
  • IA4
  • TSPAN27
• Synonyms name
  • suppression of tumorigenicity 6
  • R2 leukocyte antigen
• GenBank acession
  • U20770
• Locus
  11p11.2
• Discovery year
  1994-01-10
• Entrez gene record
  3732
• RefSeq identity
  • NM_002231
• Classification
  • Tetraspanins
  • CD molecules
• VEGA ID
  OTTHUMG00000166472

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