CD82 Antibody
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Catalog numberR30364
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.2mg/ml in 1X PBS with 50% glycerol and 0.025% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenCD82
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 0.5-1ug/ml
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NotesThe stated application concentrations are suggested starting amounts. Titration of the CD82 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis CD82 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotP27701
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PurityAntigen affinity
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DescriptionCD82(Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma(ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.
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ImmunogenAn amino acid sequence from the C-terminus of human CD82 (CRHVHSEDYSKVPKY) was used as the immunogen for this CD82 antibody.
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StorageStore the CD82 antibody at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCD82
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Short nameAnti-CD82
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to CD82
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Alternative techniqueantibodies
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Alternative to gene targetCD82 molecule, 4F9 and C33 and GR15 and IA4 and KAI1 and R2 and SAR2 and ST6 and TSPAN27, CD82 and IDBG-40873 and ENSG00000085117 and 3732, protein binding, Plasma membranes, Cd82 and IDBG-192552 and ENSMUSG00000027215 and 12521, CD82 and IDBG-636903 and ENSBTAG00000031252 and 100335281,506713
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Gene info
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Identity
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Gene
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Long gene nameCD82 molecule
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Synonyms gene
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Synonyms gene name
- kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
- CD82 antigen
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-01-10
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Entrez gene record
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RefSeq identity
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Classification
- Tetraspanins
- CD molecules
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VEGA ID