CCT2/TCP1 beta Antibody, Cy5.5 Conjugated

• Catalog number
  bs-11267R-Cy5.5
• Price
  Please ask
• Size
  0.1ml

• Long name
  CCT2/TCP1 beta Polyclonal Antibody, Cy5.5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5.5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CCT2/TCP1 beta
• Specificity
  This is a highly specific antibody against CCT2/TCP1 beta.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1). Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2). CCT2 is the β-subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3). CCT subunit levels also change throughout the cell cycle, with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4). Each CCT subunit is thought to perform a specific function during protein folding and assembly (5); CCT2 exhibits both actin and tubulin binding activities (6,3) but the exact molecular function on this subunit remains uncertain.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  675nm/694nm
• Synonyms
  CCT 2; CCT beta; CCT-beta; CCT-2; CCTB; Chaperonin containing t complex polypeptide 1 beta subunit; Chaperonin containing t complex polypeptide 1 subunit 2; Chaperonin containing TCP1 subunit 2; Chaperonin containing TCP1 subunit 2 beta; CTP:phosphocholine cytidylyltransferase 2; MGC142074; MGC142076; MGC94480; PRO1633; T complex protein 1 beta subunit; T complex protein 1 subunit beta; T-complex protein 1 subunit beta; TCP 1 beta; TCP-1-beta; TCPB_HUMAN; 99D8.1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5, Cy5.5
• Conjugated
  These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
• French translation
  anticorps

• Gene target
  CCT2/TCP1   beta   Conjugated  
• Gene symbol
  CCT2, TCP1, TRR-CCT2-1
• Short name
  Anti-CCT2/TCP1 beta
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5.5
• Alternative name
  Anti-CCT2/TCP1 beta PAb Cy5.5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1615
• Gene
  CCT2
• Long gene name
  chaperonin containing TCP1 subunit 2
• Synonyms gene name
  • chaperonin containing TCP1, subunit 2 (beta)
• Synonyms
  • Cctb
• GenBank acession
  • AF026293
• Locus
  12q15
• Discovery year
  1999-02-26
• Entrez gene record
  10576
• Pubmed identfication
  • 9819444
• RefSeq identity
  • NM_006431
• Classification
  • Chaperonins
• VEGA ID
  OTTHUMG00000169383

Gene info

• Identity
  HGNC:11655
• Gene
  TCP1
• Long gene name
  t-complex 1
• Synonyms
  • D6S230E
  • CCT1
  • Ccta
• GenBank acession
  • X52882
• Locus
  6q25.3
• Discovery year
  2001-06-22
• Entrez gene record
  6950
• Pubmed identfication
  • 3476253
  • 3653076
• RefSeq identity
  • NM_030752
• Classification
  • Chaperonins
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000015937

Gene info

• Identity
  HGNC:34744
• Gene
  TRR-CCT2-1
• Long gene name
  tRNA-Arg (anticodon CCT) 2-1
• Synonyms gene
  • TRNAR20
• Synonyms gene name
  • transfer RNA arginine 20 (anticodon CCU)
  • transfer RNA-Arg (CCT) 2-1
• Synonyms
  • tRNA-Arg-CCT-2-1
• GenBank acession
  • HG983606
• Locus
  17q25.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189181
• Classification
  • Cytoplasmic transfer RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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