anti-CCR3 Antibody

• Catalog number
  1109
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  CCR3 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, STRL33, and CX3CR1 in the chemokine receptor family were recently identified as HIV coreceptors. CCR5, CXCR4 and CCR3 are the principal receptors for HIV fusion and entry of target cells. CCR3 facilitates infection by a subset of virus. CCR3 and CCR5 promote efficient infection of microglia, the major target cells in the CNS. High levels of CCR3 and CXCR4 expression were found on the neurons from both the central and peripheral nervous systems. The CCR3 ligand, eotaxin, and an anti-CCR3 antibody inhibited HIV infection of microglia. These results indicate CCR3 plays an important role in HIV infection of CNS.
• Gene names
  CCR3 Antibody: CKR3, CD193, CMKBR3, CC-CKR-3, C-C chemokine receptor type 3, Eosinophil eotaxin receptor, C-C CKR-3
• Antibodie s label
  unlabelled serum
• Purity
  CCR3 Antibody is immunoaffinity purified IgG.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  CCR3 antibody was made against a 14 amino acid synthetic peptide from near the amino terminus of human CCR3.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  CCR3 antibody can be used for the detection of CCR3 by Western blot at 1 - 2 ug/mL.
• Suspention pH azide
  CCR3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  CCR3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  30581170
• Ncbi nr
  NP_847899
• Vial with antibody
  in solution
• NCBI GENE nr
  1232
• GENE symbol
  CCR3
• Antigene name
  chemokine (C-C motif) receptor 3
• Source
  Homo sapiens
• Protein nr
  P51677
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR3  
• Gene symbol
  CCR3
• Short name
  anti-CCR3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCCR3 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 3, CC-CKR-3 and CD193 and CKR3 and CMKBR3, CCR3 and IDBG-30125 and ENSG00000183625 and 1232, C-C chemokine receptor activity, Plasma membranes, Ccr3 and IDBG-206550 and ENSMUSG00000035448 and 12771, BT.28967 and IDBG-647811 and ENSBTAG00000001338 and 408018

Gene info

• Identity
  HGNC:1604
• Gene
  CCR3
• Long gene name
  C-C motif chemokine receptor 3
• Synonyms gene
  • CMKBR3
• Synonyms gene name
  • chemokine (C-C motif) receptor 3
• Synonyms
  • CC-CKR-3
  • CKR3
  • CD193
• GenBank acession
  • AF247361
• Locus
  3p21.31
• Discovery year
  1995-05-30
• Entrez gene record
  1232
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000133484

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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