CCR3 Antibody
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Catalog numberPA2176
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PricePlease ask
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Size0,1 mg
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Target antigenCCR3
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with specieshuman, mouse, rat
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AnalysesWB,IHC-P,ICC
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ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human CCR3(1-20aa MTTSLDTVETFGTTSYYDDV).
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the CCR3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe CCR3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundC-C chemokine receptor type 3, also called CCR3 or CKR3 is a protein that in humans is encoded by the CCR3 gene. The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. This receptor binds and responds to a variety of chemokines, including eotaxin(CCL11), eotaxin-3(CCL26), MCP-3(CCL7), MCP-4(CCL13), and RANTES(CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. Alternatively spliced transcript variants have been described.
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Related articles1. Blanchard, C., Wang, N., Stringer, K. F., Mishra, A., Fulkerson, P. C., Abonia, J. P., Jameson, S. C., Kirby, C., Konikoff, M. R., Collins, M. H., Cohen, M. B., Akers, R., Hogan, S. P., Assa'ad, A. H., Putnam, P. E., Aronow, B. J., Rothenberg, M. E. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J. Clin. Invest. 116: 536-547, 2006. 2. Takeda, A., Baffi, J. Z., Kleinman, M. E., Cho, W. G., Nozaki, M., Yamada, K., Kaneko, H., Albuquerque, R. J. C., Dridi, S., Saito, K., Raisler, B. J., Budd, S. J., and 15 others. CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature 460: 225-230, 2009.
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Gene NameCCR3
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Protein NameC-C chemokine receptor type 3
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Gene Full Namechemokine(C-C motif) receptor 3
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SynonymsB Chemokine Receptor antibody|b-chemokine receptor antibody|C C chemokine receptor type 3 antibody|C C CKR 3 antibody|C-C chemokine receptor type 3 antibody|C-C CKR-3 antibody|CC Chemokine Receptor 3 antibody|CC chemokine receptor type 3 antibody|CC CKR 3 antibody|CC R3 antibody|CC-CKR-3 antibody|CCCKR3 antibody|CCR 3 antibody|CCR-3 antibody|CCR3 antibody|CCR3_HUMAN antibody|CD 193 antibody|CD193 antibody|CD193 antigen antibody|Chemokine(C C motif) receptor 3 antibody|chemokine(C-C motif) receptor 3 antibody|Chemokine(CC) Receptor 1 Like 2 antibody|Chemokine CC Motif Receptor 3 antibody|Chemokine receptor 3 antibody|CK R3 antibody|CKR 3 antibody|CKR3 antibody|CMKB R3 antibody|CMKBR 3 antibody|CMKBR1L2 antibody|CMKBR3 antibody|Eosinophil CC Chemokine Receptor 3 antibody|Eosinophil Eotaxin Receptor antibody|Eotaxin Receptor antibody|Macrophage inflammatory protein 1 alpha receptor like 2 antibody|Macrophage Inflammatory Protein1 Alpha Receptor Like 2 antibody|MGC102841 antibody|MIP1 Alpha RL2 antibody
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Uniprot IDP51677
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCCR3
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Short nameCCR3 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative namechemokine (C-C motif) receptor 3 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetchemokine (C-C motif) receptor 3, CC-CKR-3 and CD193 and CKR3 and CMKBR3, CCR3 and IDBG-30125 and ENSG00000183625 and 1232, C-C chemokine receptor activity, Plasma membranes, Ccr3 and IDBG-206550 and ENSMUSG00000035448 and 12771, BT.28967 and IDBG-647811 and ENSBTAG00000001338 and 408018
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Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine receptor 3
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Synonyms gene
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Synonyms gene name
- chemokine (C-C motif) receptor 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-05-30
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Entrez gene record
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Classification
- C-C motif chemokine receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data