CCR3 Antibody

  • Catalog number
    R31297
  • Price
    Please ask
  • Size
    0.1mg
  • Category
    Antibody
  • Concentration
    0.5mg/ml if reconstituted with 0.2ml sterile DI water
  • Form
    Antigen affinity purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    CCR3
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, IHC-P, ICC
  • Recommended dilutions
    Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
  • Notes
    The stated application concentrations are suggested starting amounts. Titration of the CCR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This CCR3 antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    P51677
  • Purity
    Antigen affinity
  • Description
    C-C chemokine receptor type 3, also called CKR3, is a protein that in humans is encoded by the CCR3 gene. The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. This receptor binds and responds to a variety of chemokines, includingeotaxin(CCL11),eotaxin-3(CCL26),MCP-3(CCL7),MCP-4(CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. Alternatively spliced transcript variants have been described.
  • Immunogen
    An amino acid sequence from the N-terminus of human C-C chemokine receptor type 3 (MTTSLDTVETFGTTSYYDDV) was used as the immunogen for this CCR3 antibody.
  • Storage
    After reconstitution, the CCR3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    CCR3  
  • Gene symbol
    CCR3
  • Short name
    Anti-CCR3
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    Antibodies to CCR3
  • Alternative technique
    antibodies
  • Alternative to gene target
    chemokine (C-C motif) receptor 3, CC-CKR-3 and CD193 and CKR3 and CMKBR3, CCR3 and IDBG-30125 and ENSG00000183625 and 1232, C-C chemokine receptor activity, Plasma membranes, Ccr3 and IDBG-206550 and ENSMUSG00000035448 and 12771, BT.28967 and IDBG-647811 and ENSBTAG00000001338 and 408018
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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