CCR1 Antibody

• Catalog number
  F48896-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CCR1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the CCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CCR1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P32246
• Purity
  Antigen affinity
• Description
  CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
• Immunogen
  A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR1 antibody.
• Storage
  Aliquot the CCR1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR1  
• Gene symbol
  CCR1
• Short name
  Anti-CCR1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CCR1
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 1, CD191 and CKR-1 and CKR1 and CMKBR1 and HM145 and MIP1aR and SCYAR1, CCR1 and IDBG-30085 and ENSG00000163823 and 1230, chemokine (C-C motif) ligand 5 binding, Cell surfaces

Gene info

• Identity
  HGNC:1602
• Gene
  CCR1
• Long gene name
  C-C motif chemokine receptor 1
• Synonyms gene
  • SCYAR1
  • CMKBR1
• Synonyms gene name
  • chemokine (C-C motif) receptor 1
• Synonyms
  • CKR-1
  • MIP1aR
  • CD191
• Locus
  3p21.31
• Discovery year
  1993-10-14
• Entrez gene record
  1230
• Pubmed identfication
  • 7679328
• RefSeq identity
  • NM_001295
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000133451

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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