Caspase-9 Antibody
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Catalog numberbs-0050R
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PricePlease ask
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Size0.1ml
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Long nameCaspase-9 Primary Polyclonal Antibody
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Also known asCaspase-9 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenCaspase-9
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SpecificityThis is a highly specific antibody against Caspase-9.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range280-330/416
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Subcellular locationIntracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Caspase-9 subunit p35
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Gene ID number842
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Swiss ProtP55211
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenInvolved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesMCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionHuman and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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French translationanticorps
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Gene target
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Gene symbolCARD9, CASP9, CARD19
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Short nameAnti-Caspase-9
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameCaspase-9 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 9
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Synonyms gene name
- caspase recruitment domain family, member 9
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GenBank acession
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Locus
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Discovery year2001-08-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspase recruitment domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecaspase 9
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Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 19
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Synonyms gene
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Synonyms gene name
- chromosome 9 open reading frame 89
- caspase recruitment domain family, member 19
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-02-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspase recruitment domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data