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Caspase 9 Antibody, PE Conjugated

  • Catalog number
    bs-0049R-PE
  • Product name
    Caspase 9 Antibody, PE Conjugated
  • Size
    0.1ml
  • Price
    368EUR
  • Supplier
    Bioss Primary Conjugated Antibodies
  • Ask
  • Clonality
    Polyclonal
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Antigen background
    Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
  • Modification site
    None
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Long name
    Caspase 9 Polyclonal Antibody, PE Conjugated
  • Subcellular location
    Cytoplasm
  • Synonyms
    MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
  • Gene ID number
    842
  • Recommended dilutions
    FCM(1:20-100)
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Conjugation
    PE
  • Modification
    Unmodified
  • Category
    Conjugated Primary Antibodies
  • Source
    KLH conjugated synthetic peptide derived from human Caspase 9 subunit p35
  • Swiss Prot
    P55211
  • Specificity
    This is a highly specific antibody against Caspase 9.
  • Tested applications
    FCM
  • Clone
    Polyclonal antibody
  • Crossreactivity
    Human, Mouse, Rat, Dog
  • Concentration
    1ug per 1ul
  • Target Antigen
    Caspase 9
  • Immunogen_range
    20-69/416
  • Excitation Emission
    480,565nm/578nm
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene
    Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
  • Gene target
  • Short name
    Caspase 9 Antibody, PE Conjugated
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Label
    PE
  • Alternative name
    caspase 9 (Antibody to), peroxidase coupled
  • Alternative technique
    antibodies
  • Ask
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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