CACNA1B (N type) Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-10490R-A555
  • Price
    Please ask
  • Size
    100ul
  • Long name
    CACNA1B (N type) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-CACNA1B N type PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    CACNA1B N type
  • Specificity
    This is a highly specific antibody against CACNA1B N type.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    115-132/2339
  • Subcellular location
    Extracellular
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CACNA1B (N type)
  • Gene ID Number
    774
  • Swiss Prot
    Q00975
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    BIII; CACNN; DYT23; Cav2.2; CACNL1A5; Voltage-dependent N-type calcium channel subunit alpha-1B; Brain calcium channel III; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2; CACNA1B; CACH5
  • Properties
    For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 555
  • French translation
    anticorps
  • Gene target
    CACNA1B  
  • Gene symbol
    CACNA1B
  • Short name
    Anti-CACNA1B N type
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 555
  • Alternative name
    CACNA1B (N type) Polyclonal Antibody, ALEXA FLUOR 555
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    calcium voltage-gated channel subunit alpha1 B
  • Synonyms gene
  • Synonyms gene name
    • calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1995-06-01
  • Entrez gene record
    774
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Calcium voltage-gated channel alpha1 subunits
    • EF-hand domain containing
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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