CACNA1B (N type) Antibody

• Catalog number
  bs-10490R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CACNA1B (N type) Primary Polyclonal Antibody
• Also known as
  CACNA1B (N type) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CACNA1B N type
• Specificity
  This is a highly specific antibody against CACNA1B N type.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  115-132/2339
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CACNA1B (N type)
• Gene ID number
  774
• Swiss Prot
  Q00975
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BIII; CACNN; DYT23; Cav2.2; CACNL1A5; Voltage-dependent N-type calcium channel subunit alpha-1B; Brain calcium channel III; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2; CACNA1B; CACH5
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CACNA1B  
• Gene symbol
  CACNA1B
• Short name
  Anti-CACNA1B N type
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CACNA1B (N type) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1389
• Gene
  CACNA1B
• Long gene name
  calcium voltage-gated channel subunit alpha1 B
• Synonyms gene
  • CACNL1A5
• Synonyms gene name
  • calcium channel, voltage-dependent, N type, alpha 1B subunit
• Synonyms
  • Cav2.2
  • CACNN
• GenBank acession
  • AB209467
• Locus
  9q34.3
• Discovery year
  1995-06-01
• Entrez gene record
  774
• Pubmed identfication
  • 8825650
  • 16382099
• RefSeq identity
  • NM_000718
• Classification
  • Calcium voltage-gated channel alpha1 subunits
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000021002

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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