BK channel Antibody, ALEXA FLUOR 555

• Catalog number
  bs-4775R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  BK channel Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-BK channel PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  BK channel
• Specificity
  This is a highly specific antibody against BK channel.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BKCA alpha
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  subfamily M subunit alpha-1; BK channel; BKCA alpha; BKCA alpha subunit; BKTM; Calcium-activated potassium channel; Calcium-activated potassium channel subunit alpha-1; Drosophila slowpoke like; hSlo; KVCAalpha; KCa1.1; KCMA1_HUMAN; KCNMA; KCNMA1; Maxi K channel; Maxi Potassium channel alpha; MaxiK; SAKCA; SLO alpha; SLO; Slo homolog; Slo-alpha; Slo1; Slowpoke homolog.
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  channel  
• Gene symbol
  KCNMB3, KCNMB2, KCNMB4
• Short name
  Anti-BK channel
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  BK channel Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6287
• Gene
  KCNMB3
• Long gene name
  potassium calcium-activated channel subfamily M regulatory beta subunit 3
• Synonyms gene
  • KCNMB2
  • KCNMBL
• Synonyms gene name
  • potassium large conductance calcium-activated channel, subfamily M beta member 3
  • potassium channel subfamily M regulatory beta subunit 3
• Synonyms name
  • BK channel beta subunit 3
  • MaxiK channel beta-subunit 3
  • big potassium channel beta subunit 3
• GenBank acession
  • AF139471
• Locus
  3q26.32
• Discovery year
  2000-01-07
• Entrez gene record
  27094
• Pubmed identfication
  • 10585773
• Classification
  • Potassium calcium-activated channel subfamily M regulatory beta subunits
• VEGA ID
  OTTHUMG00000157337

Gene info

• Identity
  HGNC:6286
• Gene
  KCNMB2
• Long gene name
  potassium calcium-activated channel subfamily M regulatory beta subunit 2
• Synonyms gene name
  • potassium large conductance calcium-activated channel, subfamily M, beta member 2
  • potassium channel subfamily M regulatory beta subunit 2
• Synonyms name
  • BK channel beta subunit 2
  • MaxiK channel beta-subunit 2
  • big potassium channel beta subunit 2
• GenBank acession
  • AF099137
• Locus
  3q26.32
• Discovery year
  1999-06-04
• Entrez gene record
  10242
• Pubmed identfication
  • 10097176
• RefSeq identity
  • NM_181361
• Classification
  • Potassium calcium-activated channel subfamily M regulatory beta subunits
• VEGA ID
  OTTHUMG00000157264

Gene info

• Identity
  HGNC:6289
• Gene
  KCNMB4
• Long gene name
  potassium calcium-activated channel subfamily M regulatory beta subunit 4
• Synonyms gene name
  • potassium large conductance calcium-activated channel, subfamily M, beta member 4
  • potassium channel subfamily M regulatory beta subunit 4
• Synonyms name
  • BK channel beta subunit 4
  • MaxiK channel beta-subunit 4
  • big potassium channel beta subunit 4
• GenBank acession
  • AF207992
• Locus
  12q15
• Discovery year
  2000-02-02
• Entrez gene record
  27345
• Pubmed identfication
  • 10692449
  • 10828459
• RefSeq identity
  • NM_014505
• Classification
  • Potassium calcium-activated channel subfamily M regulatory beta subunits
• VEGA ID
  OTTHUMG00000167586

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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