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Target antigen
BAFF Receptor
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
Human, Mouse, Rat. No cross reactivity with other proteins.
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human BAFF Receptor(1-15aa MRRGPRSLRGRDAPA).
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the BAFF Receptor Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The BAFF Receptor Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Tumor necrosis factor receptor superfamily member 13C(TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13.1-q13.31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor(BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.
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Related articles
1. Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, Hession C, Schneider P, Sizing ID, Mullen C, Strauch K, Zafari M, Benjamin CD, Tschopp J, Browning JL, Ambrose C (Sep 2001). "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF". Science 293 (5537): 2108–11. doi:10.1126/science.1061965. PMID 11509692. 2. Entrez Gene: TNFRSF13C tumor necrosis factor receptor superfamily, member 13C". 3. Schiemann, B., Gommerman, J. L., Vora, K., Cachero, T. G., Shulga-Morskaya, S., Dobles, M., Frew, E., Scott, M. L.An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.Science293: 2111-2114, 2001.
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Gene Name
TNFRSF13C
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Protein Name
Tumor necrosis factor receptor superfamily member 13C
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Gene Full Name
tumor necrosis factor receptor superfamily, member 13C
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Synonyms
B Cell Activating Factor Receptor antibody|B-cell-activating factor receptor antibody|BAFF R antibody|BAFF receptor antibody|BAFF-R antibody|BAFFR antibody|BLyS receptor 3 antibody|BlySR3 antibody|BR 3 antibody|BR3 antibody|BROMIX antibody|CD 268 antibody|CD268 antibody|CD268 antigen antibody|CVID4 antibody|MGC138235 antibody|OTTHUMP00000028746 antibody|Prolixin antibody|TNFRSF 13C antibody|TNFRSF13C antibody|TR13C_HUMAN antibody|Tumor Necrosis Factor Receptor Subunit Member 13C antibody|Tumor necrosis factor receptor superfamily member 13C antibody
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Uniprot ID
Q96RJ3
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps
