Antithrombin (Native Protein)
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Catalog number
30 900 106
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Price
Please ask
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Size
100 µg lyophilized
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Protein type
Native
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Protein subtype
N/A
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Protein family
Inhibitor of serine proteases, Member of Serpin Family
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Protein description
Antithrombin is the most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
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Research area interests
Diseases associated with SERPINC1 include Thrombophilia Due To Antithrombin Iii Deficiency and Disseminated Intravascular Coagulation. Among its related pathways are Platelet activation, signaling and aggregation and Formation of Fibrin Clot (Clotting Cascade).
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Package form
liquid
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Tested applications
inhibitor of proteases
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Other names
Serpin Family C Member 1, SERPINC1
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Peptide sequence
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
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Available target modification
No
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Expression system
Human Blood
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Product Subtype
full length
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Active form
Yes
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Tag
untagged
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Contents
20 mM sodium phospahte buffer pH7.4; 250 mM NaCl without BSA and Azide, free of heparin
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Protein purity
>95%
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Molecular weight
65 kDa
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UniProt number
P01008
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Gene number
462
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Abbreviation
SERPINC1
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Full name
serpin family C member 1
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Other desciption
Purified from human serum.
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Purification
Mentioned in the data sheet
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PubMed citations
See the data sheet
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Warnings
For Research Use only.
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Shipping conditions
cool packs or dry ice
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Storage condition
Store at -70°C
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Technical datasheet
Contact us to receive the datasheet
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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