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anti-TrkB Antibody

  • Catalog number
    3593-100
  • Product name
    anti-TrkB Antibody
  • Size
    TrkB Antibody
  • Price
    371EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human, mouse, rat, chicken
  • Purification method:
    Affinity purified
  • Immunogene sequence:
    Synthetic peptide surrounding amino acid 810 of human TrkB
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot, Immunoprecipitation, Immunofluorescence
  • Target of this antibody:
    TrkB
  • Formulation of this antibody:
    100 µg (0.2 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
  • Alternative names of antibody target:
    NTRK2 , GP145-TrkB , TRKB , Trk-B , tyrosine receptor kinase
  • Recommended usage:
    Western blotting (0.5-4 µg/ml), immunofluorescence (5-10 µg/ml). However, the optimal concentrations should be determined individually. Trk protein exists as variably glycosylated entities with the major forms having molecular weights of 140 kDa, 110 kDa, and the unglycosylated form of 80 kDa.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3% carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting throμgh trkB such as BDNF.
  • Concentration of antibody:
    0.5 mg/ml
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-TrkB Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-TrkB (Antibody to)
  • Alternative technique
    antibodies
1. Gene info
  • Identity
  • Gene
  • Long gene name
    neurotrophic receptor tyrosine kinase 2
  • Synonyms gene name
    • neurotrophic tyrosine kinase, receptor, type 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1991-07-18
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • I-set domain containing
    • Receptor Tyrosine Kinases
  • Havana BLAST/BLAT
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