Min length of search pharse is two chars

Filters
US: (408) 780-0908 | EU: 0032 16 58 90 45 lieven@gentaur.com

anti-TLR4 Antibody

  • Catalog number
    3253-100
  • Product name
    anti-TLR4 Antibody
  • Size
    TLR4 Antibody
  • Price
    316EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Ask
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human, mouse, rat
  • Purification method:
    Affinity purified
  • Immunogene sequence:
    Synthetic peptide corresponding to residues surrounding amino acids 819 of rat TLR4
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    TLR4
  • Formulation of this antibody:
    100 µg (0.5 mg/ml) affinity purified rabbit anti-TLR4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
  • Alternative names of antibody target:
    TOLL, Toll Like Receptor 4
  • Recommended usage:
    Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~92 kDa TLR4 of rat origin. Reactivity to other species has not been tested.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    TLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.
  • Concentration of antibody:
    0.5 mg/ml
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-TLR4 Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-toll-like receptor 4 (Antibody to)
  • Alternative technique
    antibodies
  • Alternative to gene target
    toll-like receptor 4, ARMD10 and CD284 and TLR-4 and TOLL, TLR4 and IDBG-82738 and ENSG00000136869 and 7099, this GO :0000187 and activation of MAPK activity and biological process this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0001875 and lipopolysaccharide receptor activity and molecular function this GO :0002218 and activation of innate immune response and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002322 and B cell proliferation involved in immune response and biological process this GO :0002537 and nitric oxide production involved in inflammatory response and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0009617 and response to bacterium and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0010572 and positive regulation of platelet activation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016046 and detection of fungus and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032497 and detection of lipopolysaccharide and biological process this GO :0032609 and interferon-gamma production and biological process this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0032700 and negative regulation of interleukin-17 production and biological process this GO :0032707 and negative regulation of interleukin-23 production and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032732 and positive regulation of interleukin-1 production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032874 and positive regulation of stress-activated MAPK cascade and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042088 and T-helper 1 type immune response and biological process this GO :0042116 and macrophage activation and biological process this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045084 and positive regulation of interleukin-12 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045348 and positive regulation of MHC class II biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045671 and negative regulation of osteoclast differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046696 and lipopolysaccharide receptor complex and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050671 and positive regulation of lymphocyte proliferation and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0060729 and intestinal epithelial structure maintenance and biological process this GO :0060907 and positive regulation of macrophage cytokine production and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070430 and positive regulation of nucleotide-binding oli this GO merization domain containing 1 signaling pathway and biological process this GO :0070434 and positive regulation of nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, protein binding, this GO :0001530: lipopolysaccharide binding and also this GO :0001875: lipopolysaccharide receptor activity and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding, this GO :0001530: lipopolysaccharide binding, this GO :0001875: lipopolysaccharide receptor activity, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005515: protein binding, Cell surfaces, Tlr4 and IDBG-156729 and ENSMUSG00000039005 and 21898, TLR4 and IDBG-638758 and ENSBTAG00000006240 and 281536
  • Ask
1. Gene info
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
Related products
Chat with gentaur.com employee