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anti-SIRP alpha Antibody

  • Catalog number
    1125
  • Product name
    anti-SIRP alpha Antibody
  • Size
    0.02 mg, 0.1 mg
  • Price
    211.66
  • Supplier
    proscience
  • Gene info
    SIRP alpha Antibody: Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPalpha, SHPS-1, MyD-1, BIT and p84. SIRPalpha is a new gene family containing at least fifteen members. SIRPalpha is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPalpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
  • Gene names
    SIRP alpha Antibody: BIT, MFR, P84, SIRP, MYD-1, SHPS1, CD172A, PTPNS1, BIT, MYD1, Tyrosine-protein phosphatase non-receptor type substrate 1, Brain Ig-like molecule with tyrosine-based activation motifs, SHP substrate 1
  • Antibodie's label
    unlabelled serum
  • Purity
    SIRP alpha Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Spicific to
    Recognizes SIRP alpha 1, 2 and 3.
  • Antigen
    SIRP alpha antibody was made against a peptide corresponding to 17 amino acids near the carboxy terminus of human SIRP alpha 1.
  • Immuno application
    ELISA, Western Blot, immuno-cyto-chemistry
  • Antibody advice
    SIRP alpha antibody can be used for Western blot at 0.5 - 1 ug/mL. 75 - 110 kDa bands should be detected. Antibody can also be used for immunocytochemistry starting at 1 ug/mL.
  • Suspention, pH, azide
    SIRP alpha Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    SIRP alpha antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    18426911
  • Ncbi nr
    NP_542970
  • KDa
    75 - 110 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    140885
  • GENE symbol
    SIRPA
  • Antigene name
    signal-regulatory protein alpha
  • Source
    Homo sapiens
  • Protein nr
    P78324
  • Description
    The anti-SIRP alpha Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    anti-SIRP alpha Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-SIRP a (Antibody to)
  • Alternative technique
    antibodies
1. Gene info
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
Additional information
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