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anti-PTP1B Antibody (Clone 107AT531)

  • Catalog number
    3122-100
  • Product name
    anti-PTP1B Antibody (Clone 107AT531)
  • Size
    PTP1B Antibody (Clone 107AT531)
  • Price
    403EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Mouse
  • This antibody reacts with:
    Human, mouse
  • Immunogene sequence:
    Recombinant protein encoding amino acids 1-321 of human PTP1B
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    ELISA, Western blot
  • Target of this antibody:
    PTP1B
  • Formulation of this antibody:
    100 µg (0.25 mg/ml) mouse monoclonal IgG1 antibody supplied in PBS with 0.09% (W/V) sodium azide.
  • Alternative names of antibody target:
    Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTP1B
  • Recommended usage:
    The antibody can be used for ELISA (0.25 µg/ml) and Western blotting (0.5 – 2.5 µg/ml).
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Monoclonal
  • Isotype:
    Mouse IgG1
  • Clone:
    107AT531
  • Background information:
    PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.
  • Concentration of antibody:
    0.25 mg/ml
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-PTP1B Antibody (Clone 107AT531)
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-PTP1B (Antibody to) (clonality 107AT531)
  • Alternative technique
    antibodies
  • Clone name
    107AT531
1. Gene info
  • Identity
  • Gene
  • Long gene name
    protein tyrosine phosphatase, non-receptor type 1
  • Synonyms gene
  • Locus
  • Discovery year
    1991-09-13
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Protein tyrosine phosphatases, non-receptor type
  • Havana BLAST/BLAT
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