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anti-Phospho-p70 S6 Kinase Antibody

  • Catalog number
    3505-100
  • Product name
    anti-Phospho-p70 S6 Kinase Antibody
  • Size
    Phospho-p70 S6 Kinase Antibody
  • Price
    499.76
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human, mouse, rat
  • Purification method:
    Affinity purified
  • Immunogene sequence:
    Synthetic phospho-peptide surrounding amino acid Ser389 of human p70 S6 kinase
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    Phospho-p70 S6 Kinase
  • Formulation of this antibody:
    100 µg (0.5 mg/ml) affinity purified rabbit anti-Phospho-S6 (Thr389) polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
  • Alternative names of antibody target:
    RPS6KB1 , p70S6k , p70 , S6K , p70(S6K)-alpha , P70S6K , p70(S6K)-alpha , p70-alpha, Ribosomal protein S6 kinase beta-2; S6K-beta-2; S6K2; 70 kDa ribosomal protein S6 kinase 2; p70-S6K 2; P70S6K2; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; S6K-beta; p70-beta; S6 kinase-related kinase; SRK; Serine/threonine-protein kinase 14B
  • Recommended usage:
    Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects p70 S6 kinase only when phosphorylated at Thr389.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. P70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5’oligopyrimidine tract mRNAs. A second isoform, p85 S6 kinase, is derived from the same gene and is identical to p70 S6 kinase except for 23 extra residues at the N-terminus that encode a nuclear localizing signal. Both isoforms lie on a mitogen-activated signaling pathway downstream of phosphoinositide 3 kinase (PI3K) and the target of rapamycin FRAP/mTOR, and distinct from the Ras/MAP kinase cascade.
  • Concentration of antibody:
    0.5 mg/ml
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-Phospho-p70 S6 Kinase Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-phosphorilated-p70 S6 phosphorylation catalyst (Antibody to)
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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