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anti-PARP Antibody (Clone 7A10)

  • Catalog number
    3023-100
  • Product name
    anti-PARP Antibody (Clone 7A10)
  • Size
    PARP Antibody (Clone 7A10)
  • Price
    403EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Ask
  • Antibody host:
    Mouse
  • This antibody reacts with:
    Human
  • Purification method:
    N/A
  • Immunogene sequence:
    N/A
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot, Immunocytochemistry
  • Target of this antibody:
    PARP
  • Formulation of this antibody:
    N/A
  • Alternative names of antibody target:
    PARP, PPOL, ADPRT, ADPRT1, PARP-1, pADPRT-1, PARP1
  • Recommended usage:
    The antibody performs well on Western blot (1:500-1:2000) and Flow Cytometry studies (1:200-1:400).
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Monoclonal
  • Isotype:
    Mouse
  • Clone:
    7A10
  • Background information:
    PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved by many ICE-like Caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP amino-terminal DNA binding domain (24 kDa) from the carboxy-terminal catalytic domain (89 kDa). PARP helps cells to maintain their viability; cleavage of PARP facilitates cellular disassembly and serves as a marker of cells undergoing apoptosis.
  • Concentration of antibody:
    1 mg/ml
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-PARP Antibody (Clone 7A10)
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-PARP (Antibody to) (clonality 7A10)
  • Alternative technique
    antibodies
  • Clone name
    7A10
  • Ask
1. Gene info
  • Identity
  • Gene
  • Long gene name
    poly(ADP-ribose) polymerase 1
  • Synonyms gene
  • Synonyms gene name
    • ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
    • poly (ADP-ribose) polymerase family, member 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1986-01-01
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Zinc fingers PARP-type
    • Zinc fingers
    • Poly(ADP-ribose) polymerases
  • Havana BLAST/BLAT
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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