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anti-JMJD6 Antibody

  • Catalog number
    6109-50
  • Product name
    anti-JMJD6 Antibody
  • Size
    JMJD6 Antibody
  • Price
    295EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Ask
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human, chimpanzee, bovine, canine, equine, mouse, opossum
  • Purification method:
    Antigen affinity purified
  • Immunogene sequence:
    Human recombinant JMJD2A aa 127-144
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    JMJD6
  • Formulation of this antibody:
    50 µg of antibody in 100 µl PBS containing 0.05% BSA and 0.05% sodium salt.
  • Alternative names of antibody target:
    Jumonji Domain Containing 6; PTDSR
  • Recommended usage:
    Western blot: 0.25-1.0 µg/ml. However, the optimal conditions should be determined individually.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. JMJD6 is a 403 amino acid nuclear protein lysyl-hydroxylase that has been reported to have arginine demethylase activity for histone H3 at ‘Arg-2’ and histone H4 at ‘Arg-3’. JMJD6 has been sμggested to function in the differentiation of multiple organs during embryogenesis and regulate hematopoietic differentiation and macrophage cytokine responses. First identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells, JMJD6 was later indicated not to directly function in the clearance of apoptotic cells. It is ubiquitously expressed in most tissues and is upregulated in patients with chronic pancreatitis and upon cytokine treatment, but not upon TNF-α treatment.
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-JMJD6 Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-jumonji domain containing 6 (Antibody to)
  • Alternative technique
    antibodies
  • Alternative to gene target
    jumonji domain containing 6, PSR and PTDSR and PTDSR1, JMJD6 and IDBG-70010 and ENSG00000070495 and 23210, this GO :0001568 and blood vessel development and biological process this GO :0001822 and kidney development and biological process this GO :0002040 and sprouting angiogenesis and biological process this GO :0003723 and RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005506 and iron ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006397 and mRNA processing and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007507 and heart development and biological process this GO :0008380 and RNA splicing and biological process this GO :0018395 and peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine and biological process this GO :0030324 and lung development and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033746 and histone demethylase activity (H3-R2 specific) and molecular function this GO :0033749 and histone demethylase activity (H4-R3 specific) and molecular function this GO :0042116 and macrophage activation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043277 and apoptotic cell clearance and biological process this GO :0043654 and recognition of apoptotic cell and biological process this GO :0048024 and regulation of mRNA splicing, via spliceosome and biological process this GO :0048821 and erythrocyte development and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0070078 and histone H3-R2 demethylation and biological process this GO :0070079 and histone H4-R3 demethylation and biological process this GO :0070815 and peptidyl-lysine 5-dioxygenase activity and molecular function, peptidyl-lysine 5-dioxygenase activity, this GO :0003723: RNA binding and also this GO :0003727: single-stranded RNA binding and also this GO :0004872: receptor activity and also this GO :0005506: iron ion binding and also this GO :0005515: protein binding and also this GO :0033746: histone demethylase activity (H3-R2 specific) and also this GO :0033749: histone demethylase activity (H4-R3 specific) and also this GO :0042802: identical protein binding and also this GO :0070815: peptidyl-lysine 5-dioxygenase activity, this GO :0003723: RNA binding, this GO :0003727: single-stranded RNA binding, this GO :0004872: receptor activity, this GO :0005506: iron ion binding, this GO :0005515: protein binding, this GO :0033746: histone demethylase activity (H3-R2 specific), this GO :0033749: histone demethylase activity (H4-R3 specific), this GO :0042802: identical protein binding, this GO :0070815: peptidyl-lysine 5-dioxygenase activity, nuclei, Jmjd6 and IDBG-214522 and ENSMUSG00000056962 and 107817, JMJD6 and IDBG-643020 and ENSBTAG00000019153 and 508343
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1. Gene info
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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