anti-IRAK Antibody
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Catalog number1007
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoIRAK Antibody: Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa; and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
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Gene namesIRAK Antibody: IRAK, pelle, IRAK, Interleukin-1 receptor-associated kinase 1, IRAK-1
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Antibodie s labelunlabelled serum
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PurityIRAK Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toAt least three isoforms of IRAK are known to exist; this antibody will detect all three isoforms. IRAK antibody is predicted to not cross-react with other members of the IRAK protein family.
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AntigenIRAK antibody was made against a peptide corresponding to 13 amino acids near the carboxy terminus of human IRAK.
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Immuno applicationELISA, Western Blot, immuno-cyto-chemistry, immuno precipitation, immuno fluorescence
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Antibody adviceIRAK antibody can be used for Western blot at 1 ug/mL and for immunoprecipitation with 2 to 4 ug per sample. Antibody can also be used for immunocytochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideIRAK Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atIRAK antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr8928535
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Ncbi nrP51617
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KDaPredicted: 78 kDa Observed: 80 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr3654
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GENE symbolIRAK1
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Antigene nameinterleukin-1 receptor-associated kinase 1
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SourceHomo sapiens
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Protein nrP51617
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIRAK3, IRAK1
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Short nameanti-IRAK Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toIRAK (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 receptor associated kinase 3
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Synonyms gene name
- interleukin-1 receptor-associated kinase 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-07-17
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Entrez gene record
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Pubmed identfication
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Classification
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 receptor associated kinase 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-06-22
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data