anti-IRAK Antibody

• Catalog number
  1007
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  IRAK Antibody: Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa; and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
• Gene names
  IRAK Antibody: IRAK, pelle, IRAK, Interleukin-1 receptor-associated kinase 1, IRAK-1
• Antibodie s label
  unlabelled serum
• Purity
  IRAK Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  At least three isoforms of IRAK are known to exist; this antibody will detect all three isoforms. IRAK antibody is predicted to not cross-react with other members of the IRAK protein family.
• Antigen
  IRAK antibody was made against a peptide corresponding to 13 amino acids near the carboxy terminus of human IRAK.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry, immuno precipitation, immuno fluorescence
• Antibody advice
  IRAK antibody can be used for Western blot at 1 ug/mL and for immunoprecipitation with 2 to 4 ug per sample. Antibody can also be used for immunocytochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  IRAK Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  IRAK antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  8928535
• Ncbi nr
  P51617
• KDa
  Predicted: 78 kDa Observed: 80 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  3654
• GENE symbol
  IRAK1
• Antigene name
  interleukin-1 receptor-associated kinase 1
• Source
  Homo sapiens
• Protein nr
  P51617
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IRAK  
• Gene symbol
  IRAK3, IRAK1
• Short name
  anti-IRAK Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toIRAK (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17020
• Gene
  IRAK3
• Long gene name
  interleukin 1 receptor associated kinase 3
• Synonyms gene name
  • interleukin-1 receptor-associated kinase 3
• Synonyms
  • IRAK-M
• GenBank acession
  • AF113136
• Locus
  12q14.3
• Discovery year
  2002-07-17
• Entrez gene record
  11213
• Pubmed identfication
  • 10383454
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000169002

Gene info

• Identity
  HGNC:6112
• Gene
  IRAK1
• Long gene name
  interleukin 1 receptor associated kinase 1
• Synonyms
  • IRAK
  • pelle
• GenBank acession
  • L76191
• Locus
  Xq28
• Discovery year
  1998-06-22
• Entrez gene record
  3654
• Pubmed identfication
  • 9374458
  • 8599092
• VEGA ID
  OTTHUMG00000024228
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products