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anti-IL-17A Antibody

  • Catalog number
    5108-50
  • Product name
    anti-IL-17A Antibody
  • Size
    IL-17A Antibody
  • Price
    316EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human
  • Purification method:
    Affinity chromatography
  • Immunogene sequence:
    E.coli derived Recombinant Human IL-17A
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot, ELISA, Neutralization, Immunohistochemistry
  • Target of this antibody:
    IL-17A
  • Formulation of this antibody:
    A sterile filtered antibody solution in PBS, pH 7.2.
  • Alternative names of antibody target:
    CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte associated antigen 8
  • Recommended usage:
    1) WB: Use 0.1-0.2 µg/ml. The detection limit for recombinant human IL-17A is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 2) ELISA: Use 0.5 - 2.0 μg/ml (100 μl/well antibody solution) 3) Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hIL-17A (50.0 ng/ml), a concentration of 0.9-1.3 μg/ml of this antibody is required. 4) Immunohistochemistry: 0.25 µg/ml with an overnight incubation at 4°C.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells.
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-IL-17A Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-Interleukin-17A (Antibody to)
  • Alternative technique
    antibodies
1. Gene info
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