anti-GFR alpha 2 Antibody
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Catalog number
1135
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Price
Please ask
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Size
0.02 mg, 0.1 mg
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Gene info
GFR alpha 2 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRβ, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRa;-2 recently. GFRa;-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa;-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
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Gene names
GFR alpha 2 Antibody: NTNRA, RETL2, TRNR2, GDNFRB, NRTNR-ALPHA, GDNF family receptor alpha-2, GDNF receptor beta, GDNF receptor alpha-2
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Antibodie s label
unlabelled serum
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Purity
GFR alpha 2 Antibody is Antibody is DEAE purified.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Antigen
GFR alpha 2 antibody was made against a 15 amino acid peptide near the center of human GFR alpha 2.
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Immuno application
ELISA, Western Blot, immuno-cyto-chemistry
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Antibody advice
GFR alpha 2 antibody can be used for detection of GFR alpha 2 by Western blot at 1 ug/mL. A 52 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 5 ug/mL.
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Suspention pH azide
GFR alpha 2 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
GFR alpha 2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human, Mouse, Rat
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Omim nr
2145080
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Ncbi nr
AAC52036
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KDa
52 kDa
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Vial with antibody
in solution
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NCBI GENE nr
2675
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GENE symbol
GFRA2
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Antigene name
GDNF family receptor alpha 2
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Source
Homo sapiens
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Protein nr
O00451
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Description
The anti-GFR alpha 2 Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
RAPGEF5, GFRA1
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Short name
anti-GFR alpha 2 Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toGFR a 2 (antibody to-)
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Alternative technique
antibodies
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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