anti-GFR alpha 1 Antibody
-
Catalog number
1133
-
Price
Please ask
-
Size
0.02 mg, 0.1 mg
-
-
Gene info
GFR alpha 1 Antibody: Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRalpha, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently. GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRa;-1 recently. GFRa;-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRa; and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.
-
Gene names
GFR alpha 1 Antibody: GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1, GDNF family receptor alpha-1, RET ligand 1, GDNF receptor alpha-1
-
Antibodie s label
unlabelled serum
-
Purity
GFR alpha 1 Antibody is Antibody is DEAE purified.
-
Ab raised in
Rabbit
-
Type
Polyclonal
-
Immunoglobulin
IgG
-
Spicific to
GFR alpha 1 antibody is predicted to not cross-react with other members of the GFR alpha family of proteins.
-
Antigen
GFR alpha 1 antibody was made against a 14 amino acid peptide near the center of human GFR alpha 1.
-
Immuno application
ELISA, Western Blot, immuno-histo-chemistry
-
Antibody advice
GFR alpha 1 antibody can be used for detection of GFR alpha 1 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 1 ug/mL.
-
Suspention pH azide
GFR alpha 1 Antibody is supplied in PBS containing 0.02% sodium azide.
-
Keep at
GFR alpha 1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
Works with
Human, Mouse, Rat
-
Omim nr
20141405
-
Ncbi nr
P56159
-
KDa
51 kDa
-
Vial with antibody
in solution
-
Quantity per ml
1 mg/mL
-
NCBI GENE nr
2674
-
GENE symbol
GFRA1
-
Antigene name
GDNF family receptor alpha 1
-
Source
Homo sapiens
-
Protein nr
P56159
-
-
-
-
Description
The anti-GFR alpha 1 Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
RAPGEF5, GFRA1
-
Short name
anti-GFR alpha 1 Antibody
-
Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative name
Antibody toGFR a 1 (antibody to-)
-
Alternative technique
antibodies
-
Gene info
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
