anti-DR4 Antibody

• Catalog number
  1139
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  DR4 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL2, 3, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.
• Gene names
  DR4 Antibody: DR4, APO2, CD261, TRAILR1, TRAILR-1, DR4, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TRAIL receptor 1
• Antibodie s label
  unlabelled serum
• Purity
  DR4 Antibody is Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  DR4 antibody was made against a peptide corresponding to 19 amino acids near the carboxy terminus of human DR4 protein.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry
• Antibody advice
  DR4 antibody can be used for detection of DR4 expression by Western blot at 0.5 ug/mL. Antibody can also be used for immunocytochemistry starting at 10 ug/mL.
• Suspention pH azide
  DR4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  DR4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  1945072
• Ncbi nr
  AAC51226
• KDa
  57 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  8797
• GENE symbol
  TNFRSF10A
• Antigene name
  tumor necrosis factor receptor superfamily, member 10a
• Source
  Homo sapiens
• Protein nr
  O00220
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DR4  
• Gene symbol
  TNFRSF10A
• Short name
  anti-DR4 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toDR4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11904
• Gene
  TNFRSF10A
• Long gene name
  TNF receptor superfamily member 10a
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10a
• Synonyms
  • DR4
  • Apo2
  • TRAILR-1
  • CD261
  • TRAILR1
• GenBank acession
  • U90875
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8797
• Pubmed identfication
  • 9311998
  • 9082980
• RefSeq identity
  • NM_003844
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000097843

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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