anti-DR3 Antibody
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Catalog number1166
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoDR3 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kB activation.
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Gene namesDR3 Antibody: DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, WSL-LR, TNFRSF12, APO3, DR3, WSL, WSL1, UNQ455/PRO779, Tumor necrosis factor receptor superfamily member 25, Apo-3
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Antibodie s labelunlabelled serum
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PurityDR3 Antibody is Antibody is DEAE purified.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toDR3 has no cross reaction to other death receptors.
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AntigenDR3 antibody was made against a 16 amino acid peptide near the amino terminus of human DR3.
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Immuno applicationELISA, Western Blot
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Antibody adviceDR3 antibody can be used for detection of DR3 by Western blot 1 ug/mL. A 59 kDa band can be detected.
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Suspention pH azideDR3 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atDR3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse
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Omim nr37181738
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Ncbi nrAAQ88676
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KDa59 kDa
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Vial with antibodyin solution
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NCBI GENE nr8718
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GENE symbolTNFRSF25
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Antigene nametumor necrosis factor receptor superfamily, member 25
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SourceHomo sapiens
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Protein nrQ93038
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTNFRSF25
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Short nameanti-DR3 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toDR3 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 25
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
- tumor necrosis factor receptor superfamily, member 25
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data